Cellosaurus logo
expasy logo

Cellosaurus M000921 (CVCL_S808)

[Text version]
Cell line name M000921
Synonyms M00921
Accession CVCL_S808
Resource Identification Initiative To cite this cell line use: M000921 (RRID:CVCL_S808)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
From: URPP Biobank, University of Zurich; Zurich; Switzerland.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Miscellaneous: Age/sex of donor and metastatic site from personal communication of URPP Biobank.
Derived from site: Metastatic; Epigastrium; UBERON=UBERON_0035276.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=16827748; DepMap=ACH-002386).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 64Y
Category Cancer cell line
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L. Weber, Katherine L. Nathanson, Donald J. Phillips, Meenhard Herlyn, Dirk Schadendorf, Reinhard Dummer;
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=22336146; DOI=10.1111/j.1755-148X.2012.00986.x
Daniel S. Widmer, Phil F. Cheng, Ossia M. Eichhoff, Benedetta C. Belloni, Marie C. Zipser, Natalie C. Schlegel, Delphine Javelaud, Alain Mauviel, Reinhard Dummer, Keith S. Hoek;
Systematic classification of melanoma cells by phenotype-specific gene expression mapping.
Pigment Cell Melanoma Res. 25:343-353(2012)

PubMed=24581590; DOI=10.1016/j.jdermsci.2014.01.006
Samuel Gehrke, Atsushi Otsuka, Roman Huber, Barbara Meier, Magdalena Kistowska, Gabriele Fenini, Phil Cheng, Reinhard Dummer, Katrin Kerl, Emmanuel Contassot, Lars Einar French;
Metastatic melanoma cell lines do not secrete IL-1beta but promote IL-1beta production from macrophages.
J. Dermatol. Sci. 74:167-169(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S808
Cell_Model_Passport; SIDM00178
DepMap; ACH-002386
IGRhCellID; M000921
Chemistry resources PharmacoDB; M00921_876_2019
Encyclopedic resources Wikidata; Q54903405
Gene expression databases ArrayExpress; E-MTAB-3610
GEO; GSM108381
GEO; GSM108391
GEO; GSM433916
Polymorphism and mutation databases Cosmic; 1723793
Progenetix; CVCL_S808
Sequence databases EGA; EGAS00001000978
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number22