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Cellosaurus M980513 (CVCL_S675)

[Text version]
Cell line name M980513
Accession CVCL_S675
Resource Identification Initiative To cite this cell line use: M980513 (RRID:CVCL_S675)
Comments Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
From: URPP Biobank, University of Zurich; Zurich; Switzerland.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; RNAseq.
Miscellaneous: Age/sex of donor and metastatic site from personal communication of URPP Biobank.
Derived from site: Metastatic; Iliac lymph node; UBERON=UBERON_0015878.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=16827748; DepMap=ACH-002338).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 32Y
Category Cancer cell line
Publications

PubMed=16827748; DOI=10.1111/j.1600-0749.2006.00322.x
Keith S. Hoek, Natalie C. Schlegel, Patricia Brafford, Antje Sucker, Selma Ugurel, Rajiv Kumar, Barbara L. Weber, Katherine L. Nathanson, Donald J. Phillips, Meenhard Herlyn, Dirk Schadendorf, Reinhard Dummer;
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signature.
Pigment Cell Res. 19:290-302(2006)

PubMed=18245463; DOI=10.1158/0008-5472.CAN-07-2491
Keith S. Hoek, Ossia M. Eichhoff, Natalie C. Schlegel, Udo Dobbeling, Nikita Kobert, Leo Schaerer, Silvio Hemmi, Reinhard Dummer;
In vivo switching of human melanoma cells between proliferative and invasive states.
Cancer Res. 68:650-656(2008)

PubMed=22336146; DOI=10.1111/j.1755-148X.2012.00986.x
Daniel S. Widmer, Phil F. Cheng, Ossia M. Eichhoff, Benedetta C. Belloni, Marie C. Zipser, Natalie C. Schlegel, Delphine Javelaud, Alain Mauviel, Reinhard Dummer, Keith S. Hoek;
Systematic classification of melanoma cells by phenotype-specific gene expression mapping.
Pigment Cell Melanoma Res. 25:343-353(2012)

PubMed=33445472; DOI=10.3390/ncrna7010005; PMCID=PMC7838980
Marina Tusup, Phil F. Cheng, Ernesto Picardi, Austeja Raziunaite, Reinhard Dummer, Mitchell P. Levesque, Lars Einar French, Emmanuella Guenova, Thomas M. Kundig, Steve Pascolo;
Evaluation of the interplay between the ADAR editome and immunotherapy in melanoma.
Noncoding RNA 7:5.1-5.11(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S675
Cell_Model_Passport; SIDM00177
DepMap; ACH-002338
Chemistry resources PharmacoDB; M980513_880_2019
Encyclopedic resources Wikidata; Q54903663
Gene expression databases GEO; GSM108371
GEO; GSM108382
GEO; GSM4933088
Polymorphism and mutation databases Cosmic; 1723794
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number22