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Cellosaurus RBL30 (CVCL_S621)

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Cell line name RBL30
Synonyms RBL-30
Accession CVCL_S621
Resource Identification Initiative To cite this cell line use: RBL30 (RRID:CVCL_S621)
Comments Doubling time: 6 days (PubMed=2365495); 94 hours (PubMed=25326674); ~5 days (DSMZ=ACC-945).
Derived from site: In situ; Eye; UBERON=UBERON_0000970.
Sequence variations
Disease Unilateral retinoblastoma (NCIt: C8714)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 2Y6M
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-945

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133816,23
D3S135814,19
D5S81811,12
D7S82010,11
D8S11798,11
D13S31712
D16S5399,13
D18S5112,15
D19S43314
D21S1131.2,32.2
FGA19,21
Penta D9,10
Penta E5,10
TH016
TPOX8,11
vWA14,17

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Publications

PubMed=2090524; DOI=10.1111/j.1432-0436.1990.tb00479.x
Sabine Griegel, Kerstin Heise, Andrea Kindler-Rohrborn, Manfred Fedor Rajewsky;
In vitro differentiation of human retinoblastoma cells into neuronal phenotypes.
Differentiation 45:250-257(1990)

PubMed=2365495; DOI=10.1002/ijc.2910460123
Sabine Griegel, Chen Hong, Roland Frotschl, Dieter F. Hulser, Valerie Greger, Bernhard Horsthemke, Manfred Fedor Rajewsky;
Newly established human retinoblastoma cell lines exhibit an 'immortalized' but not an invasive phenotype in vitro.
Int. J. Cancer 46:125-132(1990)

PubMed=25326674; DOI=10.1007/s00418-014-1285-z
Maike Anna Busch, Claudia Philippeit, Andreas Weise, Nicole Dunker;
Re-characterization of established human retinoblastoma cell lines.
Histochem. Cell Biol. 143:325-338(2015)

PubMed=30584916; DOI=10.1016/j.yexcr.2018.12.018
Melanie Schwermer, Michaela Hiber, Sabine Dreesmann, Anja Rieb, Jessica Theissen, Thomas Herold, Alexander Schramm, Petra Temming, Laura Steenpass;
Comprehensive characterization of RB1 mutant and MYCN amplified retinoblastoma cell lines.
Exp. Cell Res. 375:92-99(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-945
Cell line databases/resources cancercelllines; CVCL_S621
Encyclopedic resources Wikidata; Q54949359
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number14