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Cellosaurus RBL20 (CVCL_S620)

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Cell line name RBL20
Accession CVCL_S620
Resource Identification Initiative To cite this cell line use: RBL20 (RRID:CVCL_S620)
Comments Doubling time: 14 days (PubMed=2365495); 1-2 weeks (Note=After thawing), ~5-8 days (Note=At later passages) (DSMZ=ACC-944).
Derived from site: In situ; Eye; UBERON=UBERON_0000970.
Sequence variations
  • Gene deletion; HGNC; HGNC:9884; RB1; Zygosity=Heterozygous (DSMZ=ACC-944).
  • Mutation; HGNC; HGNC:9884; RB1; Simple; c.607+1G>T (IVS6+1G>T); ClinVar=VCV000013093; Zygosity=Heterozygous; Note=Splice donor mutation (DSMZ=ACC-944).
Disease Bilateral retinoblastoma (NCIt: C8713)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 1Y4M
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-944

Markers:
AmelogeninX
CSF1PO12
D2S133817,20
D3S135814,17
D5S81811,12
D7S8209,10
D8S117912,14
D13S3179
D16S53911
D18S5112,14
D19S43315,16
D21S1128,33.2
FGA21,22
Penta D12
Penta E7
TH016,8
TPOX8,11
vWA16,20

Run an STR similarity search on this cell line
Publications

PubMed=2090524; DOI=10.1111/j.1432-0436.1990.tb00479.x
Sabine Griegel, Kerstin Heise, Andrea Kindler-Rohrborn, Manfred Fedor Rajewsky;
In vitro differentiation of human retinoblastoma cells into neuronal phenotypes.
Differentiation 45:250-257(1990)

PubMed=2365495; DOI=10.1002/ijc.2910460123
Sabine Griegel, Chen Hong, Roland Frotschl, Dieter F. Hulser, Valerie Greger, Bernhard Horsthemke, Manfred Fedor Rajewsky;
Newly established human retinoblastoma cell lines exhibit an 'immortalized' but not an invasive phenotype in vitro.
Int. J. Cancer 46:125-132(1990)

Cross-references
Cell line collections (Providers) DSMZ; ACC-944
Encyclopedic resources Wikidata; Q54949357
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number13