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Cellosaurus RBL15 (CVCL_S618)

[Text version]
Cell line name RBL15
Synonyms RBL-15
Accession CVCL_S618
Resource Identification Initiative To cite this cell line use: RBL15 (RRID:CVCL_S618)
Comments Doubling time: 8 days (PubMed=2365495); 45 hours (PubMed=25326674); ~5-7 days (DSMZ=ACC-943).
Derived from site: In situ; Eye; UBERON=UBERON_0000970.
Sequence variations
Disease Bilateral retinoblastoma (NCIt: C8713)
Retinoblastoma (ORDO: Orphanet_790)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 11M
Category Cancer cell line
STR profile Source(s): DSMZ=ACC-943

Markers:
AmelogeninX
CSF1PO11
D2S133819,21
D3S135815,18
D5S81811,13
D7S8208,9
D8S117910,13
D13S31712,13
D16S53911
D18S5112,18
D19S43312,15
D21S1129,30
FGA21,23
Penta D11,13
Penta E12,13
TH016,9.3
TPOX8
vWA16,17

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Publications

PubMed=2090524; DOI=10.1111/j.1432-0436.1990.tb00479.x
Sabine Griegel, Kerstin Heise, Andrea Kindler-Rohrborn, Manfred Fedor Rajewsky;
In vitro differentiation of human retinoblastoma cells into neuronal phenotypes.
Differentiation 45:250-257(1990)

PubMed=2365495; DOI=10.1002/ijc.2910460123
Sabine Griegel, Chen Hong, Roland Frotschl, Dieter F. Hulser, Valerie Greger, Bernhard Horsthemke, Manfred Fedor Rajewsky;
Newly established human retinoblastoma cell lines exhibit an 'immortalized' but not an invasive phenotype in vitro.
Int. J. Cancer 46:125-132(1990)

PubMed=7959682; DOI=10.1007/BF00211013
Valerie Greger, Nils Debus, Dietmar R. Lohmann, Wolfgang Hopping, Eberhard Passarge, Bernhard Horsthemke;
Frequency and parental origin of hypermethylated RB1 alleles in retinoblastoma.
Hum. Genet. 94:491-496(1994)

PubMed=25326674; DOI=10.1007/s00418-014-1285-z
Maike Anna Busch, Claudia Philippeit, Andreas Weise, Nicole Dunker;
Re-characterization of established human retinoblastoma cell lines.
Histochem. Cell Biol. 143:325-338(2015)

PubMed=30584916; DOI=10.1016/j.yexcr.2018.12.018
Melanie Schwermer, Michaela Hiber, Sabine Dreesmann, Anja Rieb, Jessica Theissen, Thomas Herold, Alexander Schramm, Petra Temming, Laura Steenpass;
Comprehensive characterization of RB1 mutant and MYCN amplified retinoblastoma cell lines.
Exp. Cell Res. 375:92-99(2019)

Cross-references
Cell line collections (Providers) DSMZ; ACC-943
Encyclopedic resources Wikidata; Q54949353
Entry history
Entry creation03-Feb-2014
Last entry update19-Dec-2024
Version number15