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Cellosaurus SKK-1 (CVCL_S607)

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Cell line name SKK-1
Synonyms SKK1
Accession CVCL_S607
Resource Identification Initiative To cite this cell line use: SKK-1 (RRID:CVCL_S607)
Comments Population: Japanese.
Doubling time: 32 hours (PubMed=15996938).
Karyotypic information: Has a chromosome 8 trisomy. 47,XY,add(4)(p16),+8,add(12)(p13) (PubMed=15996938).
Omics: Variations; SNP array analysis.
Miscellaneous: STR profile from personal communication of Diesch, Jeannine.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Adult acute myeloid leukemia (NCIt: C9154)
Myelodysplastic syndrome (NCIt: C3247)
Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 69Y
Category Cancer cell line
STR profile Source(s): Direct_author_submission

Markers:
AmelogeninX,Y
CSF1PO11,12
D2S133819,20
D3S135816,17
D5S81812
D7S82011,12
D8S117912,13
D13S31710
D16S5399,11
D18S5113,14
D19S43312,14
D21S1129,32
FGA21,23
TH019
TPOX9,11
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=15996938
Hiroshi Matsuoka, Tohru Murayama, Tamio Koizumi, Ryuichiro Nishimura, Ryuji Kawaguchi, Toshitaro Nakagawa;
Establishment of a human myeloid cell line with trisomy 8 derived from overt leukemia following myelodysplastic syndrome.
Haematologica 90:981-982(2005)

PubMed=27750403; DOI=10.1002/gcc.22430
Anna Palau, Mar Mallo, Laura Palomo, Ines Rodriguez-Hernandez, Jeannine Diesch, Diana Campos, Isabel Granada, Jordi Junca, Hans Gunther Drexler, Francesc Sole, Marcus Buschbeck;
Immunophenotypic, cytogenetic, and mutational characterization of cell lines derived from myelodysplastic syndrome patients after progression to acute myeloid leukemia.
Genes Chromosomes Cancer 56:243-252(2017)

PubMed=28751768; DOI=10.1038/leu.2017.240; PMCID=PMC5630086
Mohamad Jawhar, Nicole Naumann, Marcin Knut, Joannah Score, Muna Abdullah M. Ghazzawi, Bjorn Schneider, Karl-Anton Kreuzer, Michael Hallek, Hans Gunther Drexler, Joseph Chacko, Louise Wallis ...Show all 18 authors... , Alice Fabarius, Georgia Metzgeroth, Wolf-Karsten Hofmann, Andrew Chase, William J. Tapper, Andreas Reiter, Nicholas C.P. Cross; Show fewer authors
Cytogenetically cryptic ZMYM2-FLT3 and DIAPH1-PDGFRB gene fusions in myeloid neoplasms with eosinophilia.
Leukemia 31:2271-2273(2017)

PubMed=34707142; DOI=10.1038/s41598-021-00623-w; PMCID=PMC8551338
Michael Maher, Jeannine Diesch, Marguerite-Marie Le Pannerer, Marta Cabezon, Mar Mallo, Sara Vergara, Aleix Mendez Lopez, Alba Mesa Tudel, Francesc Sole, Marc Sorigue, Lurdes Zamora ...Show all 13 authors... , Isabel Granada, Marcus Buschbeck; Show fewer authors
Divergent leukaemia subclones as cellular models for testing vulnerabilities associated with gains in chromosomes 7, 8 or 18.
Sci. Rep. 11:21145.1-21145.11(2021)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S607
Encyclopedic resources Wikidata; Q54954745
Gene expression databases GEO; GSM2124118
Polymorphism and mutation databases Cosmic; 1465963
Progenetix; CVCL_S607
Entry history
Entry creation03-Feb-2014
Last entry update10-Apr-2025
Version number17