Cellosaurus cell line JoPaca-1 (CVCL

Cellosaurus JoPaca-1 (CVCL_S507)

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Cell line name

JoPaca-1

Synonyms

JOPACA-1; JOPACA1; JoPaca1

Accession

CVCL_S507

Resource Identification Initiative

To cite this cell line use: JoPaca-1 (RRID:CVCL_S507)

Comments

Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
Doubling time: 28 hours (PubMed=23152778); ~3-4 days (DSMZ=ACC-744).
Omics: Genomics; Whole exome sequencing.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.

Sequence variations

Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Heterozygous (PubMed=23152778; DepMap=ACH-001353).

Disease

Pancreatic ductal adenocarcinoma (NCIt: C9120)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Sex of cell

Male

Age at sampling

46Y

Category

Cancer cell line

STR profile

Source(s): DepMap=ACH-001353; DSMZ=ACC-744

Markers:

Amelogenin	X
CSF1PO	10
D2S1338	19
D3S1358	17,18
D5S818	11
D7S820	9,10
D8S1179	12,13
D13S317	9,12
D16S539	10
D18S51	14
D19S433	14
D21S11	30,31
FGA	22.2,24
Penta D	12
Penta E	12
TH01	9,9.3
TPOX	8
vWA	15,18

Publications

PubMed=23152778; DOI=10.1371/journal.pone.0048503; PMCID=PMC3495919
Johannes Fredebohm, Michael Boettcher, Christian Eisen, Matthias M. Gaida, Anette Heller, Shereen Keleg, Jorg Tost, Karin M. Greulich-Bode, Agnes Hotz-Wagenblatt, Mark Lathrop, Nathalia A. Giese, Jorg D. Hoheisel;
Establishment and characterization of a highly tumourigenic and cancer stem cell enriched pancreatic cancer cell line as a well defined model system.
PLoS ONE 7:e48503.1-e48503.14(2012)

Cross-references

Cell line collections (Providers)

DSMZ; ACC-744

Cell line databases/resources

cancercelllines; CVCL_S507
Cell_Model_Passport; SIDM01585
DepMap; ACH-001353
DSMZCellDive; ACC-744

Encyclopedic resources

Wikidata; Q28872926

Entry history

Entry creation

03-Feb-2014

Last entry update

10-Apr-2025

Version number