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Cellosaurus SN4741 (CVCL_S466)

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Cell line name SN4741
Accession CVCL_S466
Resource Identification Initiative To cite this cell line use: SN4741 (RRID:CVCL_S466)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA58).
Derived from site: In situ; Embryonic brain, substantia nigra; UBERON=UBERON_0006238+UBERON_0002038.
Cell type: Dopaminergic neuron; CL=CL_0000700.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: (CBA/J x C57BL/6) F2 SV40-tsA58 transgenic.
Hierarchy Children:
CVCL_F5P8 (EDITGENE SN4741-Cas9)CVCL_F5YY (EDITGENE SN4741-CopGFP)CVCL_F5RF (EDITGENE SN4741-FLUC)
Sex of cell Sex unspecified
Age at sampling 13-14FD
Category Conditionally immortalized cell line
Publications

PubMed=9870933; DOI=10.1523/JNEUROSCI.19-01-00010.1999; PMCID=PMC6782395
Jin H. Son, Hong S. Chun, Tong H. Joh, Sunghee Cho, Bruno Conti, Jong W. Lee;
Neuroprotection and neuronal differentiation studies using substantia nigra dopaminergic cells derived from transgenic mouse embryos.
J. Neurosci. 19:10-20(1999)

PubMed=22863662; DOI=10.1111/j.1582-4934.2012.01607.x; PMCID=PMC4118228
Asir Alwin Prem Anand, S. Gowri Sankar, Kokila V. Vani;
Immortalization of neuronal progenitors using SV40 large T antigen and differentiation towards dopaminergic neurons.
J. Cell. Mol. Med. 16:2592-2610(2012)

Cross-references
Cell line collections (Providers) EDITGENE; EDC00157
Anatomy/cell type resources BTO; BTO_0006140
Encyclopedic resources Wikidata; Q54955035
Entry history
Entry creation05-Nov-2013
Last entry update25-Jun-2026
Version number13