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Cellosaurus BS153 (CVCL_S444)

[Text version]
Cell line name BS153
Synonyms BS-153
Accession CVCL_S444
Resource Identification Initiative To cite this cell line use: BS153 (RRID:CVCL_S444)
Comments Characteristics: Highly overexpresses EGFR (~50 fold). Overexpress the EGFRvIII splice isoform.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
Disease Glioblastoma (NCIt: C3058)
Glioblastoma (ORDO: Orphanet_360)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_B3PI (BS153-ResE)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): PubMed=22570425

Markers:
AmelogeninX
CSF1PO10,12
D3S135817
D5S81811,13
D7S8209,11
D8S117913
D13S31712
D16S5399
D18S5112,17
D21S1128,29
FGA21,22
Penta D9,14
Penta E7
TH016,9
TPOX11
vWA15,18

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Publications

PubMed=11431328
Graham Jones, Joel Machado Jr., Adrian Merlo;
Loss of focal adhesion kinase (FAK) inhibits epidermal growth factor receptor-dependent migration and induces aggregation of NH(2)-terminal FAK in the nuclei of apoptotic glioblastoma cells.
Cancer Res. 61:4978-4981(2001)

PubMed=22570425; DOI=10.1093/neuonc/nos072; PMCID=PMC3367844
Pierre Bady, Annie-Claire Diserens, Vincent Castella, Stefanie Kalt, Karl Heinimann, Marie-France Hamou, Mauro Delorenzi, Monika E. Hegi;
DNA fingerprinting of glioma cell lines and considerations on similarity measurements.
Neuro-oncol. 14:701-711(2012)

PubMed=23877316; DOI=10.1093/neuonc/not093; PMCID=PMC3779041
Alexander Schulte, Katrin Liffers, Annegret Kathagen-Buhmann, Sabine Riethdorf, Svenja Zapf, Adrian Merlo, Katharina Kolbe, Manfred Westphal, Katrin Lamszus;
Erlotinib resistance in EGFR-amplified glioblastoma cells is associated with upregulation of EGFRvIII and PI3Kp110delta.
Neuro-oncol. 15:1289-1301(2013)

Cross-references
Encyclopedic resources Wikidata; Q54798328
Entry history
Entry creation05-Nov-2013
Last entry update19-Dec-2024
Version number10