Cellosaurus logo
expasy logo

Cellosaurus T-47D SimpleCell O-GalNAc (CVCL_S034)

[Text][XML][JSON]
Cell line name T-47D SimpleCell O-GalNAc
Synonyms T47D SimpleCell; T47D SC
Accession CVCL_S034
Resource Identification Initiative To cite this cell line use: T-47D SimpleCell O-GalNAc (RRID:CVCL_S034)
Comments Population: Caucasian.
Characteristics: Cell engineered to produce only truncated GalNAc or NeuAc-alpha-2-6-GalNAc O-glycans.
Knockout cell: Method=ZFN; HGNC; HGNC:24338; C1GALT1C1.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=23584533; DOI=10.1038/emboj.2013.79; PMCID=PMC3655468
Catharina Steentoft, Sergey Y. Vakhrushev, Hiren Jitendra Joshi, Yun Kong, Malene Bech Vester-Christensen, Katrine Ter-Borch Gram Schjoldager, Kirstine Lavrsen, Sally Dabelsteen, Nis B. Pedersen, Lara Marcos-Silva, Ramneek Gupta ...Show all 17 authors... , Eric Paul Bennett, Ulla Mandel, Soren Brunak, Hans Heugh Wandall, Steven Bruce Levery, Henrik Clausen; Show fewer authors
Precision mapping of the human O-GalNAc glycoproteome through SimpleCell technology.
EMBO J. 32:1478-1488(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_S034
Encyclopedic resources Wikidata; Q54971343
Entry history
Entry creation05-Nov-2013
Last entry update19-Dec-2024
Version number20