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Cellosaurus Dox-pDC (CVCL_RX86)

[Text version]
Cell line name Dox-pDC
Synonyms Doxycycline-inducible plasmacytoid Dendritic Cells
Accession CVCL_RX86
Resource Identification Initiative To cite this cell line use: Dox-pDC (RRID:CVCL_RX86)
Comments Characteristics: Stably proliferates by doxycycline-induction of the expression of the SV40 large T antigen. After withdrawal of doxycycline will stop proliferate and will undergo apoptosis within 3 days.
Doubling time: 2.4 +- 0.3 days (PubMed=29489861).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: Plasmacytoid dendritic cell; CL=CL_0000784.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: Rosa-rtTA-flox-Tag+ transgenic.
Sex of cell Female
Age at sampling Age unspecified
Category Conditionally immortalized cell line

PubMed=29489861; DOI=10.1371/journal.pone.0192437
Thieme S., Holzbaur A., Wiedemuth R., Binner A., Navratiel K., Anastassiadis K., Brenner S., Richter C.
The Dox-pDC -- a murine conditionally immortalized plasmacytoid dendritic cell line with native immune profile.
PLoS ONE 13:E0192437-E0192437(2018)

Encyclopedic resources Wikidata; Q54831364
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number6