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Cellosaurus BW-1100.129.237 (CVCL_RW62)

[Text version]
Cell line name BW-1100.129.237
Synonyms BWalpha-beta-; alpha(-)beta(-) BW5147; TCRalpha-beta- BW5147
Accession CVCL_RW62
Resource Identification Initiative To cite this cell line use: BW-1100.129.237 (RRID:CVCL_RW62)
Comments Group: Hybridoma fusion partner cell line.
Characteristics: Does not express functional TCR alpha and beta chains.
Doubling time: ~18 hours (PubMed=2778316).
Selected for resistance to: ChEBI; CHEBI:472805; Ouabain.
Selected for resistance to: ChEBI; CHEBI:9555; Tioguanine (6-thioguanine; 6-TG).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Thymus; UBERON=UBERON_0002370.
Disease Mouse lymphoma (NCIt: C21602)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: AKR/J.
Hierarchy Parent: CVCL_RW61 (BW-1100.129)
Children:
CVCL_RW63 (BWZ.36)
Category Cancer cell line
Publications

PubMed=2778316; DOI=10.4049/jimmunol.143.6.1822
White J., Blackman M., Bill J., Kappler J.W., Marrack P., Gold D.P., Born W.K.
Two better cell lines for making hybridomas expressing specific T cell receptors.
J. Immunol. 143:1822-1825(1989)

PubMed=32419056; DOI=10.1007/s00005-020-00579-1
White J., O'Brien R.L., Born W.K.
BW5147 and derivatives for the study of T cells and their antigen receptors.
Arch. Immunol. Ther. Exp. 68:15-15(2020)

Cross-references
Encyclopedic resources Wikidata; Q54798694
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number6