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Cellosaurus OR6 [Chlorocebus aethiops] (CVCL_RW40)

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Cell line name OR6 [Chlorocebus aethiops]
Synonyms ouaR6
Accession CVCL_RW40
Resource Identification Initiative To cite this cell line use: OR6 [Chlorocebus aethiops] (RRID:CVCL_RW40)
Comments Group: Non-human primate cell line.
Selected for resistance to: ChEBI; CHEBI_472805; Ouabain.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:799; ATP1A1.
Genetic integration: Method=Transfection/transduction; Gene=MGI; MGI:88105; Atp1a1 (Note=With p.Ile798Thr).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Species of origin Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops) (NCBI Taxonomy: 9534)
Hierarchy Parent: CVCL_0229 (CV-1)
Sex of cell Male
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=6324196; DOI=10.1073/pnas.81.5.1489; PMCID=PMC344862
Robert Levenson, Vincent R. Racaniello, Lorraine M. Albritton, David E. Housman;
Molecular cloning of the mouse ouabain-resistance gene.
Proc. Natl. Acad. Sci. U.S.A. 81:1489-1493(1984)

PubMed=2981832; DOI=10.1016/S0021-9258(20)71215-9
Leigh H. English, Jonathan Epstein, Lewis T. Cantley, David E. Housman, Robert Levenson;
Expression of an ouabain resistance gene in transfected cells Ouabain treatment induces a K+-transport system.
J. Biol. Chem. 260:1114-1119(1985)

PubMed=2826456; DOI=10.1016/S0021-9258(19)35398-0
John T. Schulz, Lewis Clayton Cantley;
CV-1 cell recipients of the mouse ouabain resistance gene express a ouabain-insensitive Na,K-ATPase after growth in cardioactive steroids.
J. Biol. Chem. 263:624-632(1988)

PubMed=8195174; DOI=10.1016/S0021-9258(17)36614-0
Lloyd G. Cantley, Mary Jo Cunha, Xiao-Mai Zhou;
Ouabain-resistant OR6 cells express the murine alpha 1-subunit of the Na,K-ATPase with a T797-I797 substitution.
J. Biol. Chem. 269:15358-15361(1994)

Cross-references
Encyclopedic resources Wikidata; Q54936488
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number7