Cellosaurus cell line WAe001-A-18 (CVCL

Cross-references
Cell line name	WAe001-A-18
Synonyms	H1-p53(R282W/R282W); 1R5; CDMLe003-A; CDMLe004-A-18
Accession	CVCL_RV18
Resource Identification Initiative	To cite this cell line use: WAe001-A-18 (RRID:CVCL_RV18)
Comments	From: Cancer Disease Modeling Laboratory, University of Texas Health Center at Houston; Houston; USA. Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358. Cell type: Embryonic stem cell; CL=CL_0002322.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple_edited; p.Arg282Trp (c.844C>T); ClinVar=VCV000012364; Zygosity=Homozygous; Note=By TALEN (PubMed=29414603).
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_9771 (WA01)
Sex of cell	Male
Age at sampling	Blastocyst stage
Category	Embryonic stem cell
Publications	PubMed=29414603; DOI=10.1016/j.scr.2018.01.035 Ruo-Ji Zhou, An Xu, Dong-Hui Wang, Dan-Dan Zhu, Helen Mata, Zi-Jun Huo, Jian Tu, Mo Liu, Alaa M.T. Mohamed, Brittany Ellis Jewell, Julian Abraham Gingold ...Show all 16 authors... , Wei-Ya Xia, Pulivarthi H. Rao, Mien-Chie Hung, Rui-Ying Zhao, Dung-Fang Lee; Show fewer authors A homozygous p53 R282W mutant human embryonic stem cell line generated using TALEN-mediated precise gene editing. Stem Cell Res. 27:131-135(2018)
Cell line databases/resources	hPSCreg; WAe001-A-18
Encyclopedic resources	Wikidata; Q54993545
Entry history
Entry creation	05-Mar-2018
Last entry update	19-Dec-2024
Version number	11