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Cellosaurus BEC2 (CVCL_RQ14)

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Cell line name BEC2
Synonyms BEC-2
Accession CVCL_RQ14
Resource Identification Initiative To cite this cell line use: BEC2 (RRID:CVCL_RQ14)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); HB-10153.
Characteristics: Was investigated under the name Mitumomab for the treatment of small cell lung carcinoma in combination with BCG vaccination.
Monoclonal antibody isotype: IgG2b, kappa.
Monoclonal antibody target: Anti-idiotypic against monoclonal antibody R24.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Hierarchy Parent: CVCL_2199 (Sp2/0-Ag14)
Category Hybridoma
Publications

PubMed=2056117; DOI=10.1172/JCI115276; PMCID=PMC296019
Paul B. Chapman, Alan N. Houghton;
Induction of IgG antibodies against GD3 ganglioside in rabbits by an anti-idiotypic monoclonal antibody.
J. Clin. Invest. 88:186-192(1991)

Patent=US5529922
Paul B. Chapman, Alan N. Houghton;
Anti-idiotypic monoclonal antibody that induces an immune response against the ganglioside GD3 and hybridoma producing said antibody.
Patent number US5529922, 25-Jun-1996

Cross-references
Encyclopedic resources Wikidata; Q54795957
Entry history
Entry creation05-Mar-2018
Last entry update14-Aug-2025
Version number5