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Cellosaurus MESO-17T (CVCL_RP27)

[Text version]
Cell line name MESO-17T
Accession CVCL_RP27
Resource Identification Initiative To cite this cell line use: MESO-17T (RRID:CVCL_RP27)
Comments Senescence: Can only be cultured for up to 15 passages before displaying signs of senescence (PubMed=26891694).
Doubling time: 53.1 hours (Note=In 2% FCS), 40.8 hours (Note=In 10% FCS) (PubMed=26891694).
Transformant: ChEBI; CHEBI_46661; Asbestos.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Lung, pleura; UBERON=UBERON_0000977.
Disease Pleural epithelioid mesothelioma (NCIt: C45662)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 72Y
Category Cancer cell line
Publications

PubMed=26891694; DOI=10.1038/cdd.2015.165; PMCID=PMC4946883
Chernova T., Sun X.-M., Powley I.R., Galavotti S., Grosso S., Murphy F.A., Miles G.J., Cresswell L., Antonov A.V., Bennett J., Nakas A., Dinsdale D., Cain K., Bushell M., Willis A.E., MacFarlane M.
Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease.
Cell Death Differ. 23:1152-1164(2016)

Cross-references
Encyclopedic resources Wikidata; Q54905290
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number8