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Cellosaurus MESO-3T (CVCL_RP21)

[Text version]
Cell line name MESO-3T
Accession CVCL_RP21
Resource Identification Initiative To cite this cell line use: MESO-3T (RRID:CVCL_RP21)
Comments Characteristics: Exhibits the ability to grow to high passage (>30) (PubMed=26891694).
Doubling time: 197.8 hours (Note=In 2% FCS), 141.6 hours (Note=In 10% FCS) (PubMed=26891694).
Transformant: ChEBI; CHEBI_46661; Asbestos.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Lung, pleura; UBERON=UBERON_0000977.
Disease Pleural epithelioid mesothelioma (NCIt: C45662)
Pleural mesothelioma (ORDO: Orphanet_50251)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): PubMed=26891694

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135818
D5S81813
D7S82010,11
D8S117911,15
D13S31711
D16S53911,13
D18S5113,14
D21S1131,33.2
FGA24
Penta D10
Penta E7,13
TH016,9.3
TPOX8,11
vWA17

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Publications

PubMed=26891694; DOI=10.1038/cdd.2015.165; PMCID=PMC4946883
Chernova T., Sun X.-M., Powley I.R., Galavotti S., Grosso S., Murphy F.A., Miles G.J., Cresswell L., Antonov A.V., Bennett J., Nakas A., Dinsdale D., Cain K., Bushell M., Willis A.E., MacFarlane M.
Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease.
Cell Death Differ. 23:1152-1164(2016)

Cross-references
Encyclopedic resources Wikidata; Q54905292
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number7