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Cellosaurus UTA.00525.LQT2 (CVCL_RN22)

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Cell line name UTA.00525.LQT2
Accession CVCL_RN22
Resource Identification Initiative To cite this cell line use: UTA.00525.LQT2 (RRID:CVCL_RN22)
Comments From: Institute of Biomedical Technology, University of Tampere; Tampere; Finland.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
Disease Long QT syndrome 2 (NCIt: C137957)
Romano-Ward syndrome (ORDO: Orphanet_101016)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_RN21 ! UTA.00514.LQT2
Sex of cell Male
Age at sampling 61Y
Category Induced pluripotent stem cell
Publications

PubMed=22052944; DOI=10.1242/dmm.008409; PMCID=PMC3291643
Anna L. Lahti, Ville J. Kujala, Hugh Chapman, Ari-Pekka Koivisto, Mari Pekkanen-Mattila, Erja Kerkela, Jari Aarne Kalevi Hyttinen, Kimmo Kaleva Kontula, Heikki Swan, Bruce R. Conklin, Shinya Yamanaka ...Show all 13 authors... , Olli Silvennoinen, Katriina Aalto-Setala; Show fewer authors
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture.
Dis. Model. Mech. 5:220-230(2012)

PubMed=23119085; DOI=10.1371/journal.pone.0048659; PMCID=PMC3485380
Marisa Ojala, Kristiina Rajala, Mari Pekkanen-Mattila, Marinka Miettinen, Heini Huhtala, Katriina Aalto-Setala;
Culture conditions affect cardiac differentiation potential of human pluripotent stem cells.
PLoS ONE 7:e48659.1-e48659.13(2012)

PubMed=27026928; DOI=10.1186/s40064-016-1889-y; PMCID=PMC4771667
Jukka Kuusela, Ville J. Kujala, Anna L. Kiviaho, Marisa Ojala, Heikki Swan, Kimmo Kaleva Kontula, Katriina Aalto-Setala;
Effects of cardioactive drugs on human induced pluripotent stem cell derived long QT syndrome cardiomyocytes.
SpringerPlus 5:234.1-234.13(2016)

Cross-references
Encyclopedic resources Wikidata; Q54992207
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number11