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Cellosaurus PDIS-6 (CVCL_RN09)

[Text version]
Cell line name PDIS-6
Synonyms LN319/hPDPN-KO
Accession CVCL_RN09
Resource Identification Initiative To cite this cell line use: PDIS-6 (RRID:CVCL_RN09)
Comments Problematic cell line: Contaminated. Parent cell line (LN-319) has been shown to be a LN-992 derivative.
Knockout cell: Method=CRISPR/Cas9; HGNC; 29602; PDPN.
Derived from sampling site: Brain; right temporal lobe.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg175His (c.524G>A); ClinVar=VCV000012374; Zygosity=Homozygous (from parent cell line).
Disease Astrocytoma (NCIt: C60781)
Astrocytoma (ORDO: Orphanet_94)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3958 (LN-319)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line

PubMed=28101903; DOI=10.1002/cam4.954
Kaneko M.K., Nakamura T., Honma R., Ogasawara S., Fujii Y., Abe S., Takagi M., Harada H., Suzuki H., Nishioka Y., Kato Y.
Development and characterization of anti-glycopeptide monoclonal antibodies against human podoplanin, using glycan-deficient cell lines generated by CRISPR/Cas9 and TALEN.
Cancer Med. 6:382-396(2017)

Encyclopedic resources Wikidata; Q54946849
Entry history
Entry creation05-Mar-2018
Last entry update21-Mar-2023
Version number5