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Cellosaurus ME-3 (CVCL_RM25)

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Cell line name ME-3
Accession CVCL_RM25
Resource Identification Initiative To cite this cell line use: ME-3 (RRID:CVCL_RM25)
Comments Population: Japanese.
Doubling time: 9-12 days (PubMed=8018932).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene fusion; HGNC; HGNC:1539; CBFB + HGNC; HGNC:7569; MYH11; Name(s)=CBFB-MYH11 (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61His (c.183A>C); ClinVar=VCV000375871; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myelomonocytic leukemia (NCIt: C7962)
Acute myelomonocytic leukemia (ORDO: Orphanet_517)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2110 (ME-1 [Human leukemia])
Children:
CVCL_G314 (ME-F3)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
Publications

PubMed=8018932; DOI=10.1182/blood.V84.1.84.84
Kohsuke Yanagisawa, Masateru Sato, Takahiko Horiuchi, Hitoshi Hasegawa, Shigeru Fujita;
Difference in response to colony-stimulating factors and involvement of protein kinase C signal transduction system in three subclones from the ME-1 cell line and two sublines.
Blood 84:84-93(1994)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Cell line databases/resources cancercelllines; CVCL_RM25
Encyclopedic resources Wikidata; Q54904903
Entry history
Entry creation05-Mar-2018
Last entry update14-Aug-2025
Version number12