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Cellosaurus Luc-LM8 (CVCL_RL04)

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Cell line name Luc-LM8
Synonyms DLM8-Luc
Accession CVCL_RL04
Resource Identification Initiative To cite this cell line use: Luc-LM8 (RRID:CVCL_RL04)
Comments Characteristics: The luciferase reporter gene is under the control of a minimal TATA promoter with multiple copies of the NF-kappaB response element.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Derived from site: In situ; Bone; UBERON=UBERON_0002481.
Disease Mouse osteosarcoma (NCIt: C24021)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C3H/HeJ.
Hierarchy Parent: CVCL_6669 (DLM8)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=22866095; DOI=10.3892/ol.2011.277; PMCID=PMC3410451
Kenjiro Sugiyasu, Katsuhiko Nanno, Noriyuki Tamai, Nobuyuki Hashimoto, Yuki Kishida, Hideki Yoshikawa, Akira Myoui;
Radio-sensitization of the murine osteosarcoma cell line LM8 with parthenolide, a natural inhibitor of NF-kappaB.
Oncol. Lett. 2:407-412(2011)

PubMed=26018200; DOI=10.1007/s11999-015-4362-2; PMCID=PMC4746149
Megan Elizabeth Aanstoos, Daniel P. Regan, Ruth J. Rose, Laura S. Chubb, Nicole P. Ehrhart;
Do mesenchymal stromal cells influence microscopic residual or metastatic osteosarcoma in a murine model?
Clin. Orthop. Relat. Res. 474:707-715(2016)

Cross-references
Encyclopedic resources Wikidata; Q54903228
Entry history
Entry creation05-Mar-2018
Last entry update14-Aug-2025
Version number8