Cellosaurus cell line SU223-B3 (CVCL

Cellosaurus SU223-B3 (CVCL_RK86)

Cross-references
Cell line name	SU223-B3
Accession	CVCL_RK86
Resource Identification Initiative	To cite this cell line use: SU223-B3 (RRID:CVCL_RK86)
Sequence variations	Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Unspecified; Note=Somatic (PubMed=28089908). Mutation; HGNC; HGNC:10729; SEMA4A; Simple; p.Tyr589His (c.1765T>C); ClinVar=VCV001418371; Zygosity=Unspecified; Note=Somatic (PubMed=28089908).
Disease	Adult acute myeloid leukemia (NCIt: C9154) Acute myeloid leukemia (ORDO: Orphanet_519)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual	CVCL_RK83 ! SU223-A2 CVCL_RK84 ! SU223-A4 CVCL_RK85 ! SU223-A7 CVCL_RK87 ! SU223-B5 CVCL_RK88 ! SU223T-4 CVCL_RK89 ! SU223T-5 CVCL_RK90 ! SU223T-6
Sex of cell	Female
Age at sampling	20Y
Category	Induced pluripotent stem cell
Publications	PubMed=28089908; DOI=10.1016/j.stem.2016.11.018; PMCID=PMC5508733 Mark P. Chao, Andrew J. Gentles, Susmita Chatterjee, Feng Lan, Andreas Reinisch, M. Ryan Corces, Seethu Xavy, Jin-Feng Shen, Daniel Haag, Soham Chanda, Rahul Sinha ...Show all 18 authors... , Rachel M. Morganti, Toshinobu Nishimura, Mohamed Ameen, Hao-Di Wu, Marius Wernig, Joseph C. Wu, Ravindra Majeti; Show fewer authors Human AML-iPSCs reacquire leukemic properties after differentiation and model clonal variation of disease. Cell Stem Cell 20:329-344.e7(2017)
Cell line databases/resources	SKIP; SKIP001722
Encyclopedic resources	Wikidata; Q54970761
Entry history
Entry creation	05-Mar-2018
Last entry update	19-Dec-2024
Version number	8