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Cellosaurus HN-SCC-131 (CVCL_RK51)

[Text version]
Cell line name HN-SCC-131
Synonyms HNSCC 131
Accession CVCL_RK51
Resource Identification Initiative To cite this cell line use: HN-SCC-131 (RRID:CVCL_RK51)
Comments Derived from site: In situ; Oral cavity, tongue, anterior part; UBERON=UBERON_0010032.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Tyr205Ser (c.614A>C); ClinVar=VCV000376683; Zygosity=Unspecified (PubMed=8339273).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=2573646; DOI=10.1080/09553008914551731
Weichselbaum R.R., Rotmensch J., Ahmed-Swan S., Beckett M.A.
Radiobiological characterization of 53 human tumor cell lines.
Int. J. Radiat. Biol. 56:553-560(1989)

PubMed=2394610; DOI=10.1016/0360-3016(90)90539-V
Weichselbaum R.R., Beckett M.A., Vijayakumar S., Simon M.A., Awan A.M., Nachman J., Panje W.R., Goldman M.E., Tybor A.G., Moran W.J., Vokes E.E., Ahmed-Swan S., Farhangi E.
Radiobiological characterization of head and neck and sarcoma cells derived from patients prior to radiotherapy.
Int. J. Radiat. Oncol. Biol. Phys. 19:313-319(1990)

PubMed=1574572; DOI=10.2307/3578273
Dunphy E.J., Beckett M.A., Thompson L.H., Weichselbaum R.R.
Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines.
Radiat. Res. 130:166-170(1992)

PubMed=8339273
Brachman D.G., Beckett M.A., Graves D., Haraf D., Vokes E.E., Weichselbaum R.R.
p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines.
Cancer Res. 53:3667-3669(1993)

DOI=10.1007/978-1-4615-2023-8_7
Weichselbaum R.R., Beckett M.A., Vokes E.E., Brachman D.G., Haraf D., Hallahan D.E., Kufe D.W.
Cellular and molecular mechanisms of radioresistance.
(In) Head and neck cancer. Cancer treatment and research, Vol. 74; Hong W.K., Weber R.S. (eds.); pp.131-140; Springer; Boston (1995)

Cross-references
Encyclopedic resources Wikidata; Q54890002
Polymorphism and mutation databases IARC_TP53; 6393
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number9