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Cellosaurus HeLa His10-SUMO-2 K0-Q87R (CVCL_RJ62)

[Text version]
Cell line name HeLa His10-SUMO-2 K0-Q87R
Synonyms HeLa His10-SUMO-2 K0
Accession CVCL_RJ62
Resource Identification Initiative To cite this cell line use: HeLa His10-SUMO-2 K0-Q87R (RRID:CVCL_RJ62)
Comments Population: African American.
Characteristics: Transfected with a decahistidine (His10) tagged lysine-deficient (K0) and Q87R SUMO2 and GFP separated by an internal ribosome entry site (IRES).
Transfected with: HGNC; 11125; SUMO2 (with p.Lys11Arg, p.Lys32Arg, p.Lys32Arg, p.Lys34Arg, p.Lys41Arg, p.Lys44Arg and p.Gln87Arg).
Transfected with: UniProtKB; P42212; GFP (with p.Phe64Leu, p.Ser65Thr and p.His231Leu = EGFP).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Sumoylated proteins analysis by proteomics.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line

PubMed=25218447; DOI=10.1038/nsmb.2890
Hendriks I.A., D'Souza R.C.J., Yang B., Verlaan-de Vries M., Mann M., Vertegaal A.C.O.
Uncovering global SUMOylation signaling networks in a site-specific manner.
Nat. Struct. Mol. Biol. 21:927-936(2014)

PubMed=28112733; DOI=10.1038/nsmb.3366
Hendriks I.A., Lyon D., Young C., Jensen L.J., Vertegaal A.C.O., Nielsen M.L.
Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
Nat. Struct. Mol. Biol. 24:325-336(2017)

Encyclopedic resources Wikidata; Q54882528
Proteomic databases PRIDE; PXD001061
PRIDE; PXD004927
PRIDE; PXD005296
Entry history
Entry creation05-Mar-2018
Last entry update05-Oct-2023
Version number6