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Cellosaurus ND40071E11 (CVCL_RH64)

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Cell line name ND40071E11
Synonyms FTLD-Tau2
Accession CVCL_RH64
Resource Identification Initiative To cite this cell line use: ND40071E11 (RRID:CVCL_RH64)
Comments Population: Caucasian.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:6893; MAPT; Simple; p.Arg798Trp (c.2392C>T) (p.Arg406Trp, c.1216C>T or p.Arg723Trp, c.2167C>T); ClinVar=VCV000014247; Zygosity=Unspecified (PubMed=27721502).
Disease Frontotemporal dementia-1 (NCIt: C217087)
Behavioral variant of frontotemporal dementia (ORDO: Orphanet_275864)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_EZ48 (ND40071)
Sex of cell Male
Age at sampling 67Y
Category Induced pluripotent stem cell
Publications

PubMed=27721502; DOI=10.1038/srep34904; PMCID=PMC5056519
Keiko Imamura, Naruhiko Sahara, Nicholas M. Kanaan, Kayoko Tsukita, Takayuki Kondo, Yumiko Kutoku, Yutaka Ohsawa, Yoshihide Sunada, Koichi Kawakami, Akitsu Hotta, Satoshi Yawata ...Show all 18 authors... , Dai Watanabe, Masato Hasegawa, John Quinn Trojanowski, Virginia Man-Yee Lee, Tetsuya Suhara, Makoto Higuchi, Haruhisa Inoue; Show fewer authors
Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons.
Sci. Rep. 6:34904.1-34904.10(2016)

Cross-references
Cell line databases/resources SKIP; SKIP001267
Encyclopedic resources Wikidata; Q54930153
Entry history
Entry creation05-Mar-2018
Last entry update27-Nov-2025
Version number12