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Cellosaurus FTD2E1 (CVCL_RH62)

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Cell line name FTD2E1
Synonyms FTLD-Tau1
Accession CVCL_RH62
Resource Identification Initiative To cite this cell line use: FTD2E1 (RRID:CVCL_RH62)
Comments Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:6893; MAPT; Simple; c.1920+14C>T (c.2091+14C>T) (c.1866+14C>T) (c.915+14C>T) (c.828+14C>T) (IVS10+14C>T); ClinVar=VCV000014248; Zygosity=Unspecified (PubMed=27721502).
Disease Frontotemporal dementia (NCIt: C84719)
Behavioral variant of frontotemporal dementia (ORDO: Orphanet_275864)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_RH63 (FTD2E1 corrected 36-20)
Sex of cell Female
Age at sampling 52Y
Category Induced pluripotent stem cell
Publications

PubMed=27721502; DOI=10.1038/srep34904; PMCID=PMC5056519
Keiko Imamura, Naruhiko Sahara, Nicholas M. Kanaan, Kayoko Tsukita, Takayuki Kondo, Yumiko Kutoku, Yutaka Ohsawa, Yoshihide Sunada, Koichi Kawakami, Akitsu Hotta, Satoshi Yawata ...Show all 18 authors... , Dai Watanabe, Masato Hasegawa, John Quinn Trojanowski, Virginia Man-Yee Lee, Tetsuya Suhara, Makoto Higuchi, Haruhisa Inoue; Show fewer authors
Calcium dysregulation contributes to neurodegeneration in FTLD patient iPSC-derived neurons.
Sci. Rep. 6:34904.1-34904.10(2016)

Cross-references
Cell line databases/resources SKIP; SKIP001265
Encyclopedic resources Wikidata; Q54835220
Entry history
Entry creation05-Mar-2018
Last entry update19-Dec-2024
Version number8