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Cellosaurus M2-1 [Rat mesothelial] (CVCL_RG50)

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Cell line name M2-1 [Rat mesothelial]
Accession CVCL_RG50
Resource Identification Initiative To cite this cell line use: M2-1 [Rat mesothelial] (RRID:CVCL_RG50)
Comments Characteristics: Has a sarcomatoid morphology (PNsarc); hypoxia low subcategory (PNsarc1) (PubMed=27129173; PubMed=32290283).
Doubling time: 44 hours (PubMed=27129173).
Transformant: ChEBI; CHEBI_46666; Crocidolite asbestos.
Omics: Proteomics.
Derived from site: In situ; Ascites; UBERON=UBERON_0007795.
Cell type: Mesothelial cell; CL=CL_0000077.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Fischer 344; RS=RS_0000215.
Sex of cell Male
Category Transformed cell line
Web pages Provider; Inserm Transfert; RT00430; https://technology-offers.inserm-transfert.com/offer/rat-mesothelial-cell-line-m2-1/
Publications

PubMed=27129173; DOI=10.18632/oncotarget.8970; PMCID=PMC5085183
David Roulois, Sophie Deshayes, Marie-Noelle Guilly, Joelle S. Nader, Charly Liddell, Myriam Robard, Philippe Hulin, Amal Ouacher, Vanessa Le Martelot, Jean-Francois Fonteneau, Marc Gregoire ...Show all 13 authors... , Christophe Blanquart, Daniel Loic Pouliquen; Show fewer authors
Characterization of preneoplastic and neoplastic rat mesothelial cell lines: the involvement of TETs, DNMTs, and 5-hydroxymethylcytosine.
Oncotarget 7:34664-34687(2016)

PubMed=32290283; DOI=10.3390/cancers12040939; PMCID=PMC7226589
Joelle S. Nader, Jordan Guillon, Coralie Petit, Alice Boissard, Florence Franconi, Stephanie Blandin, Sylvia Lambot, Marc Gregoire, Veronique Verriele-Beurrier, Beatrice Nawrocki-Raby, Philippe Birembaut ...Show all 14 authors... , Olivier Coqueret, Catherine Guette, Daniel Loic Pouliquen; Show fewer authors
S100A4 is a biomarker of tumorigenesis, EMT, invasion, and colonization of host organs in experimental malignant mesothelioma.
Cancers (Basel) 12:939.1-939.18(2020)

Cross-references
Encyclopedic resources Wikidata; Q54903506
Proteomic databases PRIDE; PXD060521
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number7