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Cellosaurus CHO EOT-3 (CVCL_RG45)

[Text version]
Cell line name CHO EOT-3
Synonyms EOT-3; EOT; PEOT; Pro-Emt(rI)Emt(rII)Oua(R)Thg(r); Emetine Ouabain Thioguanine resistant-3
Accession CVCL_RG45
Resource Identification Initiative To cite this cell line use: CHO EOT-3 (RRID:CVCL_RG45)
Comments Selected for resistance to: ChEBI; CHEBI_4781; Emetine.
Selected for resistance to: ChEBI; CHEBI_472805; Ouabain.
Selected for resistance to: ChEBI; CHEBI_9555; Tioguanine (6-thioguanine; 6-TG).
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_7182 (CHO Pro-3)
Children:
CVCL_F0DK (CHO EOT-Toyr-2)CVCL_F0F1 (CHO EOT-Toyr-6)CVCL_F0F2 (CHO EOTMA)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=217113; DOI=10.1007/BF01543160
Radhey S. Gupta, Louis Siminovitch;
Genetic and biochemical studies with the adenosine analogs toyocamycin and tubercidin: mutation at the adenosine kinase locus in Chinese hamster cells.
Somatic Cell Genet. 4:715-735(1978)

PubMed=688393; DOI=10.1016/0092-8674(78)90354-9
Radhey Shyam Gupta, David Y.-H. Chan, Louis Siminovitch;
Evidence for functional hemizygosity at the Emtr locus in CHO cells through segregation analysis.
Cell 14:1007-1013(1978)

PubMed=6312294; DOI=10.1128/mcb.3.8.1468-1477.1983; PMCID=PMC369993
Kamal Deep Mehta, Radhey S. Gupta;
Formycin B-resistant mutants of Chinese hamster ovary cells: novel genetic and biochemical phenotype affecting adenosine kinase.
Mol. Cell. Biol. 3:1468-1477(1983)

PubMed=3003929; DOI=10.1007/BF01560724
Kamal Deep Mehta, Radhey S. Gupta;
Novel mutants of CHO cells resistant to adenosine analogs and containing biochemically altered form of adenosine kinase in cell extracts.
Somat. Cell Mol. Genet. 12:21-31(1986)

Cross-references
Encyclopedic resources Wikidata; Q54832347
Entry history
Entry creation05-Mar-2018
Last entry update14-Aug-2025
Version number9