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Cellosaurus MLS (CVCL_RB32)

[Text version]
Cell line name MLS
Synonyms MLS/P
Accession CVCL_RB32
Resource Identification Initiative To cite this cell line use: MLS (RRID:CVCL_RB32)
Comments Doubling time: 24 hours (PubMed=3182331).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Disease Ovarian serous cystadenocarcinoma (NCIt: C7978)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_RB33 (MLS/ADRR2)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=3182331; DOI=10.1016/0360-3016(88)90127-7
Rofstad E.K., Sutherland R.M.
Radiation sensitivity of human ovarian carcinoma cell lines in vitro: effects of growth factors and hormones, basement membrane, and intercellular contact.
Int. J. Radiat. Oncol. Biol. Phys. 15:921-929(1988)

PubMed=2715085; DOI=10.1016/0360-3016(89)90306-4
Lee F.Y.F., Siemann D.W.
Isolation by flow cytometry of a human ovarian tumor cell subpopulation exhibiting a high glutathione content phenotype and increased resistance to adriamycin.
Int. J. Radiat. Oncol. Biol. Phys. 16:1315-1319(1989)

PubMed=2757922; DOI=10.1038/bjc.1989.7; PMCID=PMC2246982
Rofstad E.K., Sutherland R.M.
Growth and radiation sensitivity of the MLS human ovarian carcinoma cell line grown as multicellular spheroids and xenografted tumours.
Br. J. Cancer 59:28-35(1989)

PubMed=2789934; DOI=10.1038/bjc.1989.273; PMCID=PMC2247186
Lee F.Y.F., Siemann D.W., Sutherland R.M.
Changes in cellular glutathione content during adriamycin treatment in human ovarian cancer -- a possible indicator of chemosensitivity.
Br. J. Cancer 60:291-298(1989)

PubMed=1997098; DOI=10.1038/bjc.1991.52; PMCID=PMC1971782
Lee F.Y.F., Flannery D.J., Siemann D.W.
Prediction of tumour sensitivity to 4-hydroperoxycyclophosphamide by a glutathione-targeted assay.
Br. J. Cancer 63:217-222(1991)

PubMed=8194040; DOI=10.1016/0165-4608(94)90020-5
Xu J., Wang N.
Identification of chromosomal structural alterations in human ovarian carcinoma cells using combined GTG-banding and repetitive fluorescence in situ hybridization (FISH).
Cancer Genet. Cytogenet. 74:1-7(1994)

Cross-references
Encyclopedic resources Wikidata; Q54905982
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number5