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Cellosaurus MCF-10A shPARG (CVCL_RA88)

[Text version]
Cell line name MCF-10A shPARG
Synonyms shPARG MCF10A
Accession CVCL_RA88
Resource Identification Initiative To cite this cell line use: MCF-10A shPARG (RRID:CVCL_RA88)
Comments Knockout cell: Method=shRNA knockdown; HGNC; HGNC:8605; PARG.
Omics: Proteomics; PTM; Poly-ADP-ribosylation.
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008367.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0598 (MCF-10A)
Sex of cell Female
Age at sampling 36Y
Category Spontaneously immortalized cell line
Publications

PubMed=29166620; DOI=10.1016/j.celrep.2017.10.106; PMCID=PMC5728415
Yuan-Li Zhen, Ya-Jie Zhang, Yong-Hao Yu;
A cell-line-specific atlas of PARP-mediated protein Asp/Glu-ADP-ribosylation in breast cancer.
Cell Rep. 21:2326-2337(2017)

Cross-references
Encyclopedic resources Wikidata; Q54904292
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number11