• Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Glu61Ter (c.181G>T) (p.Gly75Val, c.224G>T); ClinVar=VCV000376309; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Glu69Ter (c.205G>T) (p.Gly83Val, c.248G>T); ClinVar=VCV000376308; Zygosity=Homozygous (from parent cell line).
  
• Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (from parent cell line).
  

PubMed=22389471; DOI=10.1158/1535-7163.MCT-11-0989
James G. Greger, Stephen D. Eastman, Vivian Zhang, Maureen R. Bleam, Ashley M. Hughes, Kimberly N. Smitheman, Scott H. Dickerson, Sylvie G. Laquerre, Li Liu, Tona Morgan Gilmer;
Combinations of BRAF, MEK, and PI3K/mTOR inhibitors overcome acquired resistance to the BRAF inhibitor GSK2118436 dabrafenib, mediated by NRAS or MEK mutations.
Mol. Cancer Ther. 11:909-920(2012)

Patent=US9402846
Melissa Dumble, Tona Morgan Gilmer, Rakesh Kumar, Sylvie G. Laquerre, Peter F. Lebowitz, Shannon Renae Morris;
Combination of inhibitor of B-Raf and an inhibitor of Akt in the treatment of cancer.
Patent number US9402846, 02-Aug-2016