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Cellosaurus ZZUi010-A (CVCL_QZ49)

[Text version]
Cell line name ZZUi010-A
Synonyms ZZU-iPS-AD-APP-001
Accession CVCL_QZ49
Resource Identification Initiative To cite this cell line use: ZZUi010-A (RRID:CVCL_QZ49)
Comments From: Zhengzhou University First Affiliated Hospital; Zhengzhou; China.
Population: Chinese; Han.
Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; 620; APP; Simple; p.Val717Ile (c.2149G>A); ClinVar=VCV000018088; Zygosity=Heterozygous (PubMed=29156377).
Disease Familial Alzheimer's disease, type 1 (NCIt: C146894)
Early-onset autosomal dominant Alzheimer disease (ORDO: Orphanet_1020)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 52Y
Category Induced pluripotent stem cell
STR profile Source(s): PubMed=29156377

Markers:
AmelogeninX
CSF1PO10,13
D5S8189,11
D7S82011
D13S31710,13
D16S5399,12
D21S1130,34.2
TH019
TPOX8,11
vWA17,18

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Publications

PubMed=29156377; DOI=10.1016/j.scr.2017.10.025
Wang Z.-L., Zhang P., Wang Y.-L., Shi C.-H., Jing N., Sun H.-F., Yang J., Liu Y.-T., Wen X.-J., Zhang J., Zhang S.-T., Xu Y.-M.
Establishment of induced pluripotent stem cell line (ZZUi010-A) from an Alzheimer's disease patient carrying an APP gene mutation.
Stem Cell Res. 25:213-216(2017)

Cross-references
Cell line databases/resources hPSCreg; ZZUi010-A
Biological sample resources BioSamples; SAMEA104494110
Encyclopedic resources Wikidata; Q54996171
Entry history
Entry creation05-Mar-2018
Last entry update29-Jun-2023
Version number11