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Cellosaurus A-204/PazR (CVCL_QY41)

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Cell line name A-204/PazR
Synonyms PazR/A204
Accession CVCL_QY41
Resource Identification Initiative To cite this cell line use: A-204/PazR (RRID:CVCL_QY41)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_71219; Pazopanib (Votrient).
Omics: Proteomics; PTM; Phosphorylation.
Derived from site: In situ; Muscle; UBERON=UBERON_0001630.
Sequence variations
  • Mutation; HGNC; HGNC:11103; SMARCB1; Simple; p.Gln182Alafs*28 (c.543_544delTC); Zygosity=Heterozygous (from parent cell line).
Disease Embryonal rhabdomyosarcoma (NCIt: C8971)
Embryonal rhabdomyosarcoma (ORDO: Orphanet_99757)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1058 (A-204)
Sex of cell Female
Age at sampling 1Y
Category Cancer cell line
Publications

PubMed=28842319; DOI=10.1016/j.jprot.2017.08.015; PMCID=PMC5673060
Simon Vyse, Frank McCarthy, Malgorzata Broncel, Angela Paul, Jocelyn P. Wong, Amandeep Bhamra, Paul H. Huang;
Quantitative phosphoproteomic analysis of acquired cancer drug resistance to pazopanib and dasatinib.
J. Proteomics 170:130-140(2018)

Cross-references
Encyclopedic resources Wikidata; Q54605983
Proteomic databases PRIDE; PXD005536
Entry history
Entry creation05-Mar-2018
Last entry update10-Apr-2025
Version number9