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Cellosaurus DS (CVCL_QX99)

[Text version]
Cell line name DS
Accession CVCL_QX99
Resource Identification Initiative To cite this cell line use: DS (RRID:CVCL_QX99)
Comments Population: Caucasian.
Miscellaneous: Originally assigned to be from a B-cell non-Hodgkin lymphoma, immunoblastic-type.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Disease Diffuse large B-cell lymphoma germinal center B-cell type (NCIt: C36080)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 70Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3381

Markers:
AmelogeninX
CSF1PO11,12
D5S81811,12
D7S82011
D13S31713
D16S53911,13
TH016,9.3
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=8035608
A.C. Lambrechts, Lambert C.J. Dorssers, Pauline Emily Hogenbirk-Hupkes, Ruud J.H.L.M. van Gurp, R. Baumgarten, Anne Hagemeijer, Mars B. van 't Veer, Ivo P. Touw;
Genomic organization of the translocations (8;14) and (14;18) in a new lymphoma cell line.
Leukemia 8:1164-1171(1994)

PubMed=8558920
Wilhelm Gerhard Dirks, Margarete Zaborski, Kathrin Jager, Cecile Challier, Mami Shiota, Hilmar Quentmeier, Hans Gunther Drexler;
The (2;5)(p23;q35) translocation in cell lines derived from malignant lymphomas: absence of t(2;5) in Hodgkin-analogous cell lines.
Leukemia 10:142-149(1996)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=20664054; DOI=10.1182/blood-2009-12-257378; PMCID=PMC2981542
Lan V. Pham, Archito T. Tamayo, Chang-Ping Li, Carlos E. Bueso-Ramos, Richard Joseph Ford Jr.;
An epigenetic chromatin remodeling role for NFATc1 in transcriptional regulation of growth and survival genes in diffuse large B-cell lymphomas.
Blood 116:3899-3906(2010)

PubMed=20889926; DOI=10.1182/blood-2010-06-290437; PMCID=PMC3037744
Lan V. Pham, Ling-Chen Fu, Archito T. Tamayo, Carlos E. Bueso-Ramos, Elias Drakos, Francisco Vega-Vazquez, L. Jeffrey Medeiros, Richard Joseph Ford Jr.;
Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-kappaB-inducing kinase while activating both canonical and alternative nuclear factor-kappaB pathways.
Blood 117:200-210(2011)

PubMed=26727417; DOI=10.3109/10428194.2015.1108414
Hans Gunther Drexler, Sonja Eberth, Stefan Nagel, Roderick A.F. MacLeod;
Malignant hematopoietic cell lines: in vitro models for double-hit B-cell lymphomas.
Leuk. Lymphoma 57:1015-1020(2016)

PubMed=29416618; DOI=10.18632/oncotarget.20378; PMCID=PMC5787470
Wei Liu, Juan Chen, Archito T. Tamayo, Chang-Geng Ruan, Li Li, Shou-Hao Zhou, Chan Shen, Ken H. Young, Jason Westin, Richard E. Davis, Shi-Min Hu ...Show all 14 authors... , L. Jeffrey Medeiros, Richard Joseph Ford Jr., Lan V. Pham; Show fewer authors
Preclinical efficacy and biological effects of the oral proteasome inhibitor ixazomib in diffuse large B-cell lymphoma.
Oncotarget 9:346-360(2018)

PubMed=29666304; DOI=10.1158/1078-0432.CCR-17-3004
Lan V. Pham, Sheng-Jian Huang, Hui Zhang, Jun Zhang, Taylor Bell, Shou-Hao Zhou, Elizabeth Pogue, Zhi-Yong Ding, Laura Lam, Jason Westin, R. Eric Davis ...Show all 17 authors... , Ken H. Young, L. Jeffrey Medeiros, Richard Joseph Ford Jr., Krystle Nomie, Leo Zhang, Michael Wang; Show fewer authors
Strategic therapeutic targeting to overcome venetoclax resistance in aggressive B-cell lymphomas.
Clin. Cancer Res. 24:3967-3980(2018)

Cross-references
Cell line collections (Providers) ATCC; CRL-3381
Encyclopedic resources Wikidata; Q54831425
Polymorphism and mutation databases Cosmic; 1086333
Entry history
Entry creation05-Mar-2018
Last entry update02-May-2024
Version number9