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Cellosaurus MDA-T68 (CVCL_QW83)

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Cell line name MDA-T68
Accession CVCL_QW83
Resource Identification Initiative To cite this cell line use: MDA-T68 (RRID:CVCL_QW83)
Comments Population: Caucasian.
Doubling time: ~45 hours (ATCC=CRL-3353).
Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Unspecified (PubMed=25427145).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Heterozygous; Note=In promoter (PubMed=25427145).
Disease Thyroid gland follicular carcinoma (NCIt: C8054)
Differentiated thyroid carcinoma (ORDO: Orphanet_146)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 75Y
Category Cancer cell line
STR profile Source(s): ATCC=CRL-3353; PubMed=25427145

Markers:
AmelogeninX,Y
CSF1PO11
D5S81812
D7S8209,12
D13S3179,12
D16S53911,12
TH017
TPOX8,12
vWA18

Run an STR similarity search on this cell line
Publications

PubMed=25427145; DOI=10.1210/jc.2014-2624; PMCID=PMC4318904
Ying C. Henderson, Soon-Hyun Ahn, Junsun Ryu, Yun-Yun Chen, Michelle D. Williams, Adel K. El-Naggar, Mihai Gagea, Rebecca E. Schweppe, Bryan R. Haugen, Stephen Y. Lai, Gary L. Clayman;
Development and characterization of six new human papillary thyroid carcinoma cell lines.
J. Clin. Endocrinol. Metab. 100:E243-E252(2015)

Cross-references
Cell line collections (Providers) ATCC; CRL-3353
Cell line databases/resources cancercelllines; CVCL_QW83
Encyclopedic resources Wikidata; Q54904662
Polymorphism and mutation databases Cosmic; 2612756
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number13