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Cellosaurus MDA-T22 (CVCL_QW80)

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Cell line name MDA-T22
Accession CVCL_QW80
Resource Identification Initiative To cite this cell line use: MDA-T22 (RRID:CVCL_QW80)
Comments Derived from site: In situ; Thyroid gland; UBERON=UBERON_0002046.
Sequence variations
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=25427145).
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Unspecified (PubMed=25427145).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Heterozygous; Note=In promoter (PubMed=25427145).
Disease Thyroid gland papillary carcinoma (NCIt: C4035)
Differentiated thyroid carcinoma (ORDO: Orphanet_146)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 79Y
Category Cancer cell line
STR profile Source(s): PubMed=25427145

Markers:
AmelogeninX
CSF1PO11,12
D7S8209,13
D13S31711,14
D16S5399,11
TH016,9
TPOX8,10
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=25427145; DOI=10.1210/jc.2014-2624; PMCID=PMC4318904
Ying C. Henderson, Soon-Hyun Ahn, Junsun Ryu, Yun-Yun Chen, Michelle D. Williams, Adel K. El-Naggar, Mihai Gagea, Rebecca E. Schweppe, Bryan R. Haugen, Stephen Y. Lai, Gary L. Clayman;
Development and characterization of six new human papillary thyroid carcinoma cell lines.
J. Clin. Endocrinol. Metab. 100:E243-E252(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_QW80
Encyclopedic resources Wikidata; Q54904659
Polymorphism and mutation databases Cosmic; 2612752
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number13