| Cell line name |
TC-CTR-shRNA |
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| Accession |
CVCL_QW71 |
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| Resource Identification Initiative |
To cite this cell line use: TC-CTR-shRNA (RRID:CVCL_QW71) |
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| Comments |
Population: Caucasian.
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Bone, humerus; UBERON=UBERON_0000976. |
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| Sequence variations |
- Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
- Gene fusion; HGNC; HGNC:3508; EWSR1 + HGNC; HGNC:3749; FLI1; Name(s)=EWSR1-FLI1, EWS-FLI1 (from parent cell line).
- Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:9588; PTEN; Simple; p.Arg233Ter (c.697C>T); ClinVar=VCV000007813; Zygosity=Heterozygous (from parent cell line).
- Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg213Ter (c.637C>T); ClinVar=VCV000043590; Zygosity=Unspecified (from parent cell line).
|
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| Disease |
Ewing sarcoma (NCIt: C4817)
Ewing sarcoma (ORDO: Orphanet_319) |
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| Species of origin |
Homo sapiens (Human)
(NCBI Taxonomy: 9606) |
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| Hierarchy |
Parent: CVCL_2213 (TC-71) |
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| Sex of cell |
Male |
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| Age at sampling |
22Y |
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| Category |
Cancer cell line |
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| Publications | PubMed=20197622; DOI=10.1172/JCI36667; PMCID=PMC2827943
Anna Rocchi, Maria Cristina Manara, Marika Sciandra, Diana Zambelli, Filippo Nardi, Giordano Nicoletti, Cecilia Garofalo, Stefania Meschini, Annalisa Astolfi, Mario P. Colombo, Stephen Lee Lessnick ...Show all 13 authors... , Piero Picci, Katia Scotlandi; Show fewer authors
CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesis.
J. Clin. Invest. 120:668-680(2010) |
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| Cross-references |
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| Cell line databases/resources |
cancercelllines; CVCL_QW71
|
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| Encyclopedic resources |
Wikidata; Q54971827
|
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| Gene expression databases |
GEO; GSM278141
GEO; GSM278142
|
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| Entry history |
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| Entry creation | 15-Nov-2017 |
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| Last entry update | 10-Apr-2025 |
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| Version number | 13 |
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