• Gene fusion; HGNC; HGNC:7135; AFF1 + HGNC; HGNC:7132; KMT2A; Name(s)=KMT2A-AFF1, MLL-AFF1, ALL-1/AF4; Note=In frame (PubMed=1423625; PubMed=8358709).
  

PubMed=1648979; DOI=10.1182/blood.V78.1.94.94
Amos Cohen, Tom Grunberger, Wilma Vanek, Ian David Dube, Paul J. Doherty, Michelle Letarte, Chaim M. Roifman, Melvin Harris Freedman;
Constitutive expression and role in growth regulation of interleukin-1 and multiple cytokine receptors in a biphenotypic leukemic cell line.
Blood 78:94-102(1991)

PubMed=1423625; DOI=10.1016/0092-8674(92)90603-A
Yan-Song Gu, Tatsuya Nakamura, Hansjuerg Alder, Rajendra Prasad, Ora Canaani, Giuseppe Cimino, Carlo Maria Croce, Eli Canaani;
The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene.
Cell 71:701-708(1992)

PubMed=8358709
Joanne M. Hilden, Chien-Shing Chen, Roderick Moore, Joy Frestedt, John H. Kersey;
Heterogeneity in MLL/AF-4 fusion messenger RNA detected by the polymerase chain reaction in t(4;11) acute leukemia.
Cancer Res. 53:3853-3856(1993)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

PubMed=14671638; DOI=10.1038/sj.leu.2403236
Hans Gunther Drexler, Hilmar Quentmeier, Roderick A.F. MacLeod;
Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations.
Leukemia 18:227-232(2004)