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Cellosaurus ALL-2 (CVCL_QW62)

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Cell line name ALL-2
Accession CVCL_QW62
Resource Identification Initiative To cite this cell line use: ALL-2 (RRID:CVCL_QW62)
Sequence variations
  • Gene fusion; HGNC; HGNC:7135; AFF1 + HGNC; HGNC:7132; KMT2A; Name(s)=KMT2A-AFF1, MLL-AFF1, ALL-1/AF4 (from child cell line ALL-2B).
Disease Childhood B acute lymphoblastic leukemia (NCIt: C9140)
B acute lymphoblastic leukemia with t(v;11q23.3) MLL rearranged (NCIt: C80342)
B-lymphoblastic leukemia/lymphoma with t(v;11q23.3) (ORDO: Orphanet_585918)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_QW67 (ALL-2B)
Sex of cell Female
Age at sampling 10Y
Category Cancer cell line
Publications

PubMed=3496132; DOI=10.1182/blood.V70.1.192.192
Beverly Lange, Mauro Valtieri, Daniela Santoli, Daniele Caracciolo, Fulvio Mavilio, Ingrid Gemperlein, Constance A. Griffin, Beverly S. Emanuel, Janet Finan, Peter Carey Nowell, Giovanni Rovera;
Growth factor requirements of childhood acute leukemia: establishment of GM-CSF-dependent cell lines.
Blood 70:192-199(1987)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Encyclopedic resources Wikidata; Q54749169
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number14