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Cellosaurus ALL-1 (CVCL_QW61)

[Text version]
Cell line name ALL-1
Accession CVCL_QW61
Resource Identification Initiative To cite this cell line use: ALL-1 (RRID:CVCL_QW61)
Comments Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; 76; ABL1 + HGNC; 1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=10071072).
Disease Childhood B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C68659)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=3513189; DOI=10.1073/pnas.83.6.1807
Erikson J., Griffin C.A., ar-Rushdi A., Valtieri M., Hoxie J.A., Finan J., Emanuel B.S., Rovera G., Nowell P.C., Croce C.M.
Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia.
Proc. Natl. Acad. Sci. U.S.A. 83:1807-1811(1986)

PubMed=2825022; DOI=10.1038/330386a0
Fainstein E., Marcelle C., Rosner A., Canaani E., Gale R.P., Dreazen O., Smith S.D., Croce C.M.
A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukaemia.
Nature 330:386-388(1987)

PubMed=3496132; DOI=10.1182/blood.V70.1.192.192
Lange B., Valtieri M., Santoli D., Caracciolo D., Mavilio F., Gemperlein I., Griffin C.A., Emanuel B.S., Finan J., Nowell P.C., Rovera G.
Growth factor requirements of childhood acute leukemia: establishment of GM-CSF-dependent cell lines.
Blood 70:192-199(1987)

PubMed=2039829; DOI=10.1182/blood.V77.11.2463.2463
Cesano A., O'Connor R., Lange B., Finan J., Rovera G., Santoli D.
Homing and progression patterns of childhood acute lymphoblastic leukemias in severe combined immunodeficiency mice.
Blood 77:2463-2474(1991)

PubMed=10071072; DOI=10.1016/s0145-2126(98)00171-4
Drexler H.G., MacLeod R.A.F., Uphoff C.C.
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Drexler H.G.
The leukemia-lymphoma cell line factsbook.
(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)

Cross-references
Encyclopedic resources Wikidata; Q54749167
Polymorphism and mutation databases Cosmic; 2348804
Entry history
Entry creation15-Nov-2017
Last entry update29-Jun-2023
Version number9