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Cellosaurus ALL-1 (CVCL_QW61)

[Text version]
Cell line name ALL-1
Accession CVCL_QW61
Resource Identification Initiative To cite this cell line use: ALL-1 (RRID:CVCL_QW61)
Comments Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Sequence variations
  • Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (PubMed=10071072; PubMed=10576511).
Disease Childhood B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1 (NCIt: C68659)
B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) (ORDO: Orphanet_585909)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 7Y
Category Cancer cell line
Publications

PubMed=3513189; DOI=10.1073/pnas.83.6.1807; PMCID=PMC323173
Jan Erikson, Constance A. Griffin, Abbas ar-Rushdi, Mauro Valtieri, James A. Hoxie, Janet Finan, Beverly S. Emanuel, Giovanni Rovera, Peter Carey Nowell, Carlo Maria Croce;
Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia.
Proc. Natl. Acad. Sci. U.S.A. 83:1807-1811(1986)

PubMed=2825022; DOI=10.1038/330386a0
E. Fainstein, Christophe Marcelle, Amalia Rosner, Eli Canaani, Robert Peter Gale, Orna Dreazen, Stephen D. Smith, Carlo Maria Croce;
A new fused transcript in Philadelphia chromosome positive acute lymphocytic leukaemia.
Nature 330:386-388(1987)

PubMed=3496132; DOI=10.1182/blood.V70.1.192.192
Beverly Lange, Mauro Valtieri, Daniela Santoli, Daniele Caracciolo, Fulvio Mavilio, Ingrid Gemperlein, Constance A. Griffin, Beverly S. Emanuel, Janet Finan, Peter Carey Nowell, Giovanni Rovera;
Growth factor requirements of childhood acute leukemia: establishment of GM-CSF-dependent cell lines.
Blood 70:192-199(1987)

PubMed=2039829; DOI=10.1182/blood.V77.11.2463.2463
Alessandra Cesano, Rosemary O'Connor, Beverly Lange, Janet Finan, Giovanni Rovera, Daniela Santoli;
Homing and progression patterns of childhood acute lymphoblastic leukemias in severe combined immunodeficiency mice.
Blood 77:2463-2474(1991)

PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4
Hans Gunther Drexler, Roderick A.F. MacLeod, Cord C. Uphoff;
Leukemia cell lines: in vitro models for the study of Philadelphia chromosome-positive leukemia.
Leuk. Res. 23:207-215(1999)

PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9
Cord C. Uphoff, Silke Habig, Severine Fombonne, Yoshinobu Matsuo, Hans Gunther Drexler;
ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.
Leuk. Res. 23:1055-1060(1999)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Encyclopedic resources Wikidata; Q54749167
Polymorphism and mutation databases Cosmic; 2348804
Entry history
Entry creation15-Nov-2017
Last entry update19-Dec-2024
Version number11