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Cellosaurus HEK293T SMARCB1-/- (CVCL_QW54)

[Text version]
Cell line name HEK293T SMARCB1-/-
Synonyms SMARCB1-/- HEK293T; BAF47-knockout HEK293T
Accession CVCL_QW54
Resource Identification Initiative To cite this cell line use: HEK293T SMARCB1-/- (RRID:CVCL_QW54)
Comments Knockout cell: Method=CRISPR/Cas9; HGNC; 11103; SMARCB1.
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 28285; Adenovirus 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=tsA].
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0063 (HEK293T)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=28945250; DOI=10.1038/ng.3958
Nakayama R.T., Pulice J.L., Valencia A.M., McBride M.J., McKenzie Z.M., Gillespie M.A., Ku W.L., Teng M.-X., Cui K.-R., Williams R.T., Cassel S.H., Qing H., Widmer C.J., Demetri G.D., Irizarry R.A., Zhao K.-J., Ranish J.A., Kadoch C.
SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters.
Nat. Genet. 49:1613-1623(2017)

Cross-references
Encyclopedic resources Wikidata; Q54882490
Entry history
Entry creation15-Nov-2017
Last entry update05-Oct-2023
Version number7