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Cellosaurus BT054 (CVCL_N707)

[Text version]
Cell line name BT054
Synonyms BT54
Accession CVCL_N707
Resource Identification Initiative To cite this cell line use: BT054 (RRID:CVCL_N707)
Comments Group: Cancer stem cell line.
Derived from site: In situ; Brain; UBERON=UBERON_0000955.
Sequence variations
  • Mutation; HGNC; 5382; IDH1; Simple; p.Arg132His (c.395G>A); ClinVar=VCV000156444; Zygosity=Unspecified (PubMed=20388696).
Disease Anaplastic oligodendroglioma (NCIt: C4326)
Anaplastic oligodendroglioma (ORDO: Orphanet_251630)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 49Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,12
D7S8209,11
D13S31712,14
D16S53911,12
TH016,7
TPOX9,11
vWA16,17

Run an STR similarity search on this cell line
Publications

PubMed=20388696; DOI=10.1093/neuonc/noq031
Kelly J.J.P., Blough M.D., Stechishin O.D.M., Chan J.A.W., Beauchamp D.C., Perizzolo M., Demetrick D.J., Steele L., Auer R.N., Hader W.J., Westgate M.R., Parney I.F., Jenkins R.B., Cairncross J.G., Weiss S.
Oligodendroglioma cell lines containing t(1;19)(q10;p10).
Neuro-oncol. 12:745-755(2010)

PubMed=30153289; DOI=10.1371/journal.pone.0202860
Yuan A.L., Ricks C.B., Bohm A.K., Lun X.-Q., Maxwell L., Safdar S., Bukhari S., Gerber A., Sayeed W., Bering E.A., Pedersen H., Chan J.A.W., Shen Y.-Q., Marra M., Kaplan D.R., Mason W., Goodman L.D., Ezhilarasan R., Kaufmann A.B., Cabral M., Robbins S.M., Senger D.L., Cahill D.P., Sulman E.P., Cairncross J.G., Blough M.D.
ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts.
PLoS ONE 13:E0202860-E0202860(2018)

Cross-references
Cell line collections (Providers) ATCC; CRL-3416
Cell line databases/resources cancercelllines; CVCL_N707
Encyclopedic resources Wikidata; Q54798483
Entry history
Entry creation05-Nov-2013
Last entry update05-Oct-2023
Version number13