Cellosaurus cell line Wa-2 (CVCL

Cellosaurus Wa-2 (CVCL_M847)

Cross-references
Cell line name	Wa-2
Synonyms	Wa2
Accession	CVCL_M847
Resource Identification Initiative	To cite this cell line use: Wa-2 (RRID:CVCL_M847)
Comments	Doubling time: 53 hours (Note=At 50th passage) (PubMed=2180563). Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Gene deletion; HGNC; 11103; SMARCB1; Zygosity=Heterozygous (PubMed=9671307).
Disease	Extrarenal rhabdoid tumor (NCIt: C6586) Rhabdoid tumor (ORDO: Orphanet_69077)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	1Y5M
Category	Cancer cell line
Publications	PubMed=2180563 Handgretinger R., Kimmig A., Koscielniak E., Schmidt D., Rudolph G., Wolburg H., Paulus W., Schilbach-Stuckle K., Ottenlinger C., Menrad A., Sproll M., Bruchelt G., Dopfer R., Treuner J., Niethammer D. Establishment and characterization of a cell line (Wa-2) derived from an extrarenal rhabdoid tumor. Cancer Res. 50:2177-2182(1990) PubMed=9671307; DOI=10.1038/28212 Versteege I., Sevenet N., Lange J., Rousseau-Merck M.-F., Ambros P.F., Handgretinger R., Aurias A., Delattre O. Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer. Nature 394:203-206(1998) PubMed=10397258 Rousseau-Merck M.-F., Versteege I., Legrand I., Couturier J., Mairal A., Delattre O., Aurias A. hSNF5/INI1 inactivation is mainly associated with homozygous deletions and mitotic recombinations in rhabdoid tumors. Cancer Res. 59:3152-3156(1999)
Encyclopedic resources	Wikidata; Q54993500
Polymorphism and mutation databases	Cosmic; 802253
Entry history
Entry creation	05-Nov-2013
Last entry update	29-Jun-2023
Version number	10