Cellosaurus cell line NOS-1 [Human HNSCC] (CVCL

Cellosaurus NOS-1 [Human HNSCC] (CVCL_M837)

Cross-references
Cell line name	NOS-1 [Human HNSCC]
Accession	CVCL_M837
Resource Identification Initiative	To cite this cell line use: NOS-1 [Human HNSCC] (RRID:CVCL_M837)
Comments	Population: Japanese. Doubling time: 16.1 hours (Note=At 100th passage) (PubMed=11291288; PubMed=11337272). Derived from site: In situ; Oral cavity, gingiva; UBERON=UBERON_0001828.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg248Trp (c.742C>T); ClinVar=VCV000012347; Zygosity=Unspecified (PubMed=11337272).
Disease	Lower gingival squamous cell carcinoma (NCIt: C8171) Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	47Y
Category	Cancer cell line
Publications	PubMed=11291288 Zheng-Wen Ji, Naohisa Oku, Takahide Komori; Establishment of a novel human squamous cell carcinoma cell line from oral primary tumor by geneticin treatment. Kobe J. Med. Sci. 46:137-145(2000) PubMed=11337272; DOI=10.1016/S1368-8375(00)00088-9 Zheng-Wen Ji, Naohisa Oku, Masahiro Umeda, Takahide Komori; Establishment of an oral squamous cell carcinoma cell line (NOS-1) exhibiting amplification of the erbB-1 oncogene and point mutation of p53 tumor suppressor gene: its biological characteristics and animal model of local invasion by orthotopic transplantation of the cell line. Oral Oncol. 37:386-392(2001)
Cell line databases/resources	cancercelllines; CVCL_M837
Encyclopedic resources	Wikidata; Q54930910
Polymorphism and mutation databases	IARC_TP53; 17855
Entry history
Entry creation	05-Nov-2013
Last entry update	19-Dec-2024
Version number	16