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Cellosaurus LiSa-2 (CVCL_M821)

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Cell line name LiSa-2
Synonyms LISA-2
Accession CVCL_M821
Resource Identification Initiative To cite this cell line use: LiSa-2 (RRID:CVCL_M821)
Comments Characteristics: Can be differentiated into mature adipocytes.
Omics: Transcriptomics; Microarray.
Omics: Variations; SNP array analysis.
Derived from site: Metastatic; Retroperitoneal space; UBERON=UBERON_0003693.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu348Ser (c.1043T>C); Zygosity=Unspecified (PubMed=26643872).
Disease Pleomorphic liposarcoma (NCIt: C3705)
Pleomorphic liposarcoma (ORDO: Orphanet_99969)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 53Y
Category Cancer cell line
Publications

PubMed=11093810; DOI=10.1002/1097-0215(20001215)88:6<889::AID-IJC8>3.0.CO;2-N
Martin Wabitsch, Silke Bruderlein, Ingo Melzner, Mike Braun, Gunhild Mechtersheimer, Peter Moller;
LiSa-2, a novel human liposarcoma cell line with a high capacity for terminal adipose differentiation.
Int. J. Cancer 88:889-894(2000)

PubMed=18283285; DOI=10.1038/ijo.2008.10
Esther Antoinette van Beek, Arjen H.F. Bakker, Philip M. Kruyt, Carolien Vink, Wim H.M. Saris, Nicole L.W. Franssen-van Hal, Jaap Keijer;
Comparative expression analysis of isolated human adipocytes and the human adipose cell lines LiSa-2 and PAZ6.
Int. J. Obes. 32:912-921(2008)

PubMed=20197395; DOI=10.1158/1535-7163.MCT-09-0705; PMCID=PMC2837520
Marcy A. Mitchell, Jay E. Johnson, Kara Pascarelli, Neil Beeharry, Maria Chiourea, Sarantis Gagos, Dina Chelouche Lev, Margaret von Mehren, David Kipling, Dominique Broccoli;
Doxorubicin resistance in a novel in vitro model of human pleomorphic liposarcoma associated with alternative lengthening of telomeres.
Mol. Cancer Ther. 9:682-692(2010)

PubMed=22911243; DOI=10.1155/2012/148614; PMCID=PMC3403520
Eva Wessel Stratford, Russell Castro, Jeanette Daffinrud, Magne Skarn, Silje Lauvrak, Else Munthe, Ola Myklebost;
Characterization of liposarcoma cell lines for preclinical and biological studies.
Sarcoma 2012:148614.1-148614.9(2012)

PubMed=24726063; DOI=10.1186/1756-9966-33-33; PMCID=PMC4022359
Christian Koelsche, Marcus Renner, Wolfgang Hartmann, Regine Brandt, Burkhard Lehner, Nina Waldburger, Ingo Alldinger, Thomas Schmitt, Gerlinde Egerer, Roland Penzel, Eva Wardelmann ...Show all 14 authors... , Peter Schirmacher, Andreas von Deimling, Gunhild Mechtersheimer; Show fewer authors
TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities.
J. Exp. Clin. Cancer Res. 33:33.1-33.8(2014)

PubMed=26643872; DOI=10.18632/oncotarget.6464; PMCID=PMC4767443
Deepika Kanojia, Yasunobu Nagata, Manoj Garg, Dhong Hyun Lee, Aiko Sato, Kenichi Yoshida, Yusuke Sato, Masashi Sanada, Anand Mayakonda, Christoph Bartenhagen, Hans-Ulrich Klein ...Show all 28 authors... , Ngan B. Doan, Jonathan William Said, S. Mohith, Swetha Gunasekar, Yuichi Shiraishi, Kenichi Chiba, Hiroko Tanaka, Satoru Miyano, Ola Myklebost, Henry He Yang, Martin Dugas, Leonardo Andres Meza-Zepeda, Allan W. Silberman, Charles Forscher, Jeffrey W. Tyner, Seishi Ogawa, Harold Phillip Koeffler; Show fewer authors
Genomic landscape of liposarcoma.
Oncotarget 6:42429-42444(2015)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M821
Encyclopedic resources Wikidata; Q54902640
Gene expression databases GEO; GSE3643
GEO; GSM482515
Polymorphism and mutation databases Cosmic; 2307721
Cosmic; 2800522
Progenetix; CVCL_M821
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number19