Cellosaurus cell line SCC-12B.2 (CVCL

Cellosaurus SCC-12B.2 (CVCL_M672)

Cross-references
Cell line name	SCC-12B.2
Synonyms	SCC-12B2; SCC-12 B.2; SCC12B2
Accession	CVCL_M672
Resource Identification Initiative	To cite this cell line use: SCC-12B.2 (RRID:CVCL_M672)
Comments	Derived from site: In situ; Face, skin; UBERON=UBERON_1000021.
Sequence variations	Mutation; HGNC; HGNC:5173; HRAS; Simple; p.Gly12Leu; Zygosity=Unspecified (from parent cell line). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Val216Gly (c.647T>G); ClinVar=VCV000376671; Zygosity=Unspecified (from parent cell line).
Disease	Skin squamous cell carcinoma (NCIt: C4819)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_4027 (SCC-12B)
Sex of cell	Male
Age at sampling	60Y
Category	Cancer cell line
Web pages	Provider; BWH dermatology; -; https://dermatology.bwh.harvard.edu/docs/Cell-Culture-Core-Cell-Lines.pdf
Publications	PubMed=3182330; DOI=10.1016/0360-3016(88)90125-3 Jeffrey L. Schwartz, Jacob Rotmensch, Susan Giovanazzi, Marvin B. Cohen, Ralph R. Weichselbaum; Faster repair of DNA double-strand breaks in radioresistant human tumor cells. Int. J. Radiat. Oncol. Biol. Phys. 15:907-912(1988) PubMed=3360658; DOI=10.1016/0360-3016(88)90013-2 Ralph R. Weichselbaum, Michael A. Beckett, William K. Dahlberg, Anatoly Dritschilo; Heterogeneity of radiation response of a parent human epidermoid carcinoma cell line and four clones. Int. J. Radiat. Oncol. Biol. Phys. 14:907-912(1988)
Cell line databases/resources	cancercelllines; CVCL_M672
Encyclopedic resources	Wikidata; Q54952329
Entry history
Entry creation	05-Nov-2013
Last entry update	10-Apr-2025
Version number	13