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Cellosaurus MA-1 [Human contaminated lymphoma] (CVCL_M665)

[Text version]
Cell line name MA-1 [Human contaminated lymphoma]
Synonyms Ma-1
Accession CVCL_M665
Resource Identification Initiative To cite this cell line use: MA-1 [Human contaminated lymphoma] (RRID:CVCL_M665)
Comments Problematic cell line: Contaminated. Shown to be a Pfeiffer derivative (PubMed=23907998) and not a mucosa-associated lymphoid tissue (MALT) lymphoma cell line. This finding is disputed by the original authors (PubMed=24285409).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00471.
Population: Caucasian.
Derived from site: In situ; Pleural effusion; UBERON=UBERON_0000175.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Arg1171Cys (c.3511C>T); ClinVar=VCV000133518; Zygosity=Heterozygous (from parent cell line).
Disease Diffuse large B-cell lymphoma germinal center B-cell type (NCIt: C36080)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3326 (Pfeiffer)
Sex of cell Male
Age at sampling Adult
Category Cancer cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=21837708; DOI=10.1002/gcc.20910
Sung-Hsin Kuo, Wen-Hui Weng, Zhi-Hua Chen, Ping-Ning Hsu, Ming-Shiang Wu, Chung-Wu Lin, Huei-Jiuan Jeng, Kun-Huei Yeh, Hui-Jen Tsai, Li-Tzong Chen, Ann-Lii Cheng;
Establishment of a novel MALT lymphoma cell line, Ma-1, from a patient with t(14;18)(q32;q21)-positive Helicobacter pylori-independent gastric MALT lymphoma.
Genes Chromosomes Cancer 50:908-921(2011)

PubMed=23508748; DOI=10.1002/gcc.22051
Sung-Hsin Kuo, Kun-Huei Yeh, Ann-Lii Cheng, Wen-Hui Weng, Li-Tzong Chen;
No evidence of IGH-MALT1-translocation in the Ma-1 cell line -- a reply.
Genes Chromosomes Cancer 52:593-594(2013)

PubMed=23508779; DOI=10.1002/gcc.22052
Lucia Flossbach, Thomas F.E. Barth, Peter Moller;
No evidence of IGH-MALT1 translocation in the Ma-1 cell line.
Genes Chromosomes Cancer 52:591-592(2013)

PubMed=23907998; DOI=10.1002/gcc.22094
Amanda Capes-Davis, Christine Alston-Roberts, Liz Kerrigan, Yvonne A. Reid, Tanya Barrett, Edward C. Burnett, Jim R. Cooper, Robert Ian Freshney, Lyn E. Healy, Arihiro Kohara, Christopher T. Korch ...Show all 18 authors... , John R.W. Masters, Yukio Nakamura, Raymond Whiting Nims, Douglas R. Storts, Wilhelm Gerhard Dirks, Roderick A.F. MacLeod, Hans Gunther Drexler; Show fewer authors
Beware imposters: MA-1, a novel MALT lymphoma cell line, is misidentified and corresponds to Pfeiffer, a diffuse large B-cell lymphoma cell line.
Genes Chromosomes Cancer 52:986-988(2013)

PubMed=24285409; DOI=10.1002/gcc.22122
Sung-Hsin Kuo, Hui-Jen Tsai, Wen-Hui Weng, Chi-Cheng Li, Kun-Huei Yeh, Li-Tzong Chen, Ann-Lii Cheng;
Comments on: 'beware imposters: MA-1, a novel MALT lymphoma cell line, is misidentified and corresponds to Pfeiffer, a diffuse large B-cell lymphoma cell line-A'. Reply: despite the same 8-code STR, MA-1 and Pfeiffer are cytogenetically diverse.
Genes Chromosomes Cancer 53:211-213(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M665
Biological sample resources BioSample; SAMN03151897
Encyclopedic resources Wikidata; Q54903677
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number22