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Cellosaurus Elijah (CVCL_M653)

[Text version]
Cell line name Elijah
Synonyms ELIJAH; ELI-BL; ELI BL; Eli-BL; Eli BL; ELI; Eli
Accession CVCL_M653
Resource Identification Initiative To cite this cell line use: Elijah (RRID:CVCL_M653)
Comments Population: African; Kenyan.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Variations; Array-based CGH.
Misspelling: Elija; Note=Occasionally.
Derived from site: In situ; Bone, jaw; UBERON=UBERON_0001708.
Cell type: B-cell; CL=CL_0000236.
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
Publications

PubMed=2985508; DOI=10.1002/ijc.2910350404
Rowe M., Rooney C.M., Rickinson A.B., Lenoir G.M., Rupani H., Moss D.J., Stein H., Epstein M.A.
Distinctions between endemic and sporadic forms of Epstein-Barr virus-positive Burkitt's lymphoma.
Int. J. Cancer 35:435-441(1985)

PubMed=2943927; DOI=10.1093/jnci/77.3.681
Rooney C.M., Gregory C.D., Rowe M., Finerty S., Edwards C.F., Rupani H., Rickinson A.B.
Endemic Burkitt's lymphoma: phenotypic analysis of tumor biopsy cells and of derived tumor cell lines.
J. Natl. Cancer Inst. 77:681-687(1986)

PubMed=2824665; DOI=10.1099/0022-1317-68-11-2853
Young L.S., Yao Q.-Y., Rooney C.M., Sculley T.B., Moss D.J., Rupani H., Laux G., Bornkamm G.-W., Rickinson A.B.
New type B isolates of Epstein-Barr virus from Burkitt's lymphoma and from normal individuals in endemic areas.
J. Gen. Virol. 68:2853-2862(1987)

PubMed=2898508; DOI=10.1084/jem.167.6.1811; PMCID=PMC2189677
Gregory C.D., Murray R.J., Edwards C.F., Rickinson A.B.
Downregulation of cell adhesion molecules LFA-3 and ICAM-1 in Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell escape from virus-specific T cell surveillance.
J. Exp. Med. 167:1811-1824(1988)

PubMed=16960149; DOI=10.1182/blood-2006-06-026500
Mestre-Escorihuela C., Rubio-Moscardo F., Richter J.A., Siebert R., Climent J., Fresquet V., Beltran E., Agirre X., Marugan I., Marin M., Rosenwald A., Sugimoto K.-j., Wheat L.M., Karran E.L., Garcia J.F., Sanchez-Verde L., Prosper F., Staudt L.M., Pinkel D., Dyer M.J.S., Martinez-Climent J.A.
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Blood 109:271-280(2007)

PubMed=28960205; DOI=10.1038/cdd.2017.150; PMCID=PMC5762840
Fitzsimmons L., Boyce A.J., Wei W.-B., Chang C., Croom-Carter D.S.G., Tierney R.J., Herold M.J., Bell A.I., Strasser A., Kelly G.L., Rowe M.
Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.
Cell Death Differ. 25:241-254(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M653
Encyclopedic resources Wikidata; Q54832250
Gene expression databases GEO; GSM115809
Polymorphism and mutation databases Cosmic; 2297022
Progenetix; CVCL_M653
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number21