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Cellosaurus Elijah (CVCL_M653)

[Text version]
Cell line name Elijah
Synonyms ELIJAH; ELI-BL; ELI BL; Eli-BL; Eli BL; ELI; Eli
Accession CVCL_M653
Resource Identification Initiative To cite this cell line use: Elijah (RRID:CVCL_M653)
Comments Population: African; Kenyan.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Variations; Array-based CGH.
Misspelling: Elija; Note=Occasionally.
Derived from site: In situ; Bone, jaw; UBERON=UBERON_0001708.
Cell type: B-cell; CL=CL_0000236.
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 3Y
Category Cancer cell line
Publications

PubMed=2985508; DOI=10.1002/ijc.2910350404
Martin Rowe, Cliona M. Rooney, Alan Bernard Rickinson, Gilbert Marcel Lenoir, Hitesh Rupani, Denis J. Moss, Harald Stein, Michael Anthony Epstein;
Distinctions between endemic and sporadic forms of Epstein-Barr virus-positive Burkitt's lymphoma.
Int. J. Cancer 35:435-441(1985)

PubMed=2943927; DOI=10.1093/jnci/77.3.681
Cliona M. Rooney, Christopher D. Gregory, Martin Rowe, Susan Finerty, Carole F. Edwards, Hitesh Rupani, Alan Bernard Rickinson;
Endemic Burkitt's lymphoma: phenotypic analysis of tumor biopsy cells and of derived tumor cell lines.
J. Natl. Cancer Inst. 77:681-687(1986)

PubMed=2824665; DOI=10.1099/0022-1317-68-11-2853
Lawrence S. Young, Qing-Yun Yao, Cliona M. Rooney, Tom B. Sculley, Denis J. Moss, Hitesh Rupani, Gerhard Laux, Georg-Wilhelm Bornkamm, Alan Bernard Rickinson;
New type B isolates of Epstein-Barr virus from Burkitt's lymphoma and from normal individuals in endemic areas.
J. Gen. Virol. 68:2853-2862(1987)

PubMed=2898508; DOI=10.1084/jem.167.6.1811; PMCID=PMC2189677
Christopher D. Gregory, Ruth J. Murray, Carole F. Edwards, Alan Bernard Rickinson;
Downregulation of cell adhesion molecules LFA-3 and ICAM-1 in Epstein-Barr virus-positive Burkitt's lymphoma underlies tumor cell escape from virus-specific T cell surveillance.
J. Exp. Med. 167:1811-1824(1988)

PubMed=16960149; DOI=10.1182/blood-2006-06-026500
Cinta Mestre-Escorihuela, Fanny Rubio-Moscardo, Jose A. Richter, Reiner Siebert, Joan Climent, Vicente Fresquet, Elena Beltran, Xabier Agirre, Isabel Marugan, Miguel Marin, Andreas Rosenwald ...Show all 21 authors... , Kei-ji Sugimoto, Luise M. Wheat, E. Loraine Karran, Juan Fernando Garcia Garcia, Lydia Sanchez-Verde, Felipe Prosper, Louis Michael Staudt, Daniel Pinkel, Martin John Swinnerton Dyer, Jose Angel Martinez-Climent; Show fewer authors
Homozygous deletions localize novel tumor suppressor genes in B-cell lymphomas.
Blood 109:271-280(2007)

PubMed=28960205; DOI=10.1038/cdd.2017.150; PMCID=PMC5762840
Leah Fitzsimmons, Andrew J. Boyce, Wen-Bin Wei, Catherine Chang, Debbie S.G. Croom-Carter, Rosemary J. Tierney, Marco J. Herold, Andrew I. Bell, Andreas Strasser, Gemma L. Kelly, Martin Rowe;
Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.
Cell Death Differ. 25:241-254(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M653
Encyclopedic resources Wikidata; Q54832250
Gene expression databases GEO; GSM115809
Polymorphism and mutation databases Cosmic; 2297022
Progenetix; CVCL_M653
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number21