Cellosaurus cell line BL-12 (CVCL

Cellosaurus BL-12 (CVCL_M640)

Cross-references
Cell line name	BL-12
Synonyms	BL12; BL 12; IARC/BL12; IARC/BL 12; CIARC-BL12; IARC BL12; IARC BL 12
Accession	CVCL_M640
Resource Identification Initiative	To cite this cell line use: BL-12 (RRID:CVCL_M640)
Comments	From: International Agency of Research on Cancer (IARC); Lyon; France. Population: African. Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV). Caution: Indicated as originating from a male patient in PubMed=3027441 and PubMed=3934070 and from a female patient in PubMed=6825067. Cell type: B-cell; CL=CL_0000236.
Sequence variations	Mutation; HGNC; HGNC:7553; MYC; Simple; p.Thr73Ile (c.218C>T); ClinVar=VCV000376300; Zygosity=Unspecified (PubMed=8108117).
Disease	EBV-related Burkitt lymphoma (NCIt: C27694) Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	6Y
Category	Cancer cell line
Publications	PubMed=6825067; DOI=10.1016/0165-4608(83)90138-3 Alain Bernheim, Roland Berger, Gilbert Marcel Lenoir; Cytogenetic studies on Burkitt's lymphoma cell lines. Cancer Genet. Cytogenet. 8:223-229(1983) PubMed=3934070 Gilbert Marcel Lenoir, Michele Vuillaume, Colette Bonnardel; The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma. IARC Sci. Publ. 60:309-318(1985) PubMed=3027441; DOI=10.1093/jnci/78.2.235 Jacques H.M. Cohen, Jean-Pierre Revillard, Jean-Pierre Magaud, Gilbert Marcel Lenoir, Michele Vuillaume, Anne-Marie Manel, Claude Vincent, Paul-Andre Bryon; B-cell maturation stages of Burkitt's lymphoma cell lines according to Epstein-Barr virus status and type of chromosome translocation. J. Natl. Cancer Inst. 78:235-242(1987) PubMed=8108117 Thomas Albert, Birgit Urlbauer, Franz Kohlhuber, Bettina Hammersen, Dirk Eick; Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines. Oncogene 9:759-763(1994)
Cell line databases/resources	cancercelllines; CVCL_M640
Encyclopedic resources	Wikidata; Q54797102
Polymorphism and mutation databases	Cosmic; 2804858
Entry history
Entry creation	05-Nov-2013
Last entry update	19-Dec-2024
Version number	16