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Cellosaurus BL-12 (CVCL_M640)

[Text version]
Cell line name BL-12
Synonyms BL12; BL 12; IARC/BL12; IARC/BL 12; CIARC-BL12; IARC BL12; IARC BL 12
Accession CVCL_M640
Resource Identification Initiative To cite this cell line use: BL-12 (RRID:CVCL_M640)
Comments From: International Agency of Research on Cancer (IARC); Lyon; France.
Population: African.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Caution: Indicated as originating from a male patient in PubMed=3027441 and PubMed=3934070 and from a female patient in PubMed=6825067.
Cell type: B-cell; CL=CL_0000236.
Sequence variations
  • Mutation; HGNC; 7553; MYC; Simple; p.Thr73Ile (c.218C>T); ClinVar=VCV000376300; Zygosity=Unspecified (PubMed=8108117).
Disease EBV-related Burkitt lymphoma (NCIt: C27694)
Burkitt lymphoma (ORDO: Orphanet_543)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 6Y
Category Cancer cell line
Publications

PubMed=6825067; DOI=10.1016/0165-4608(83)90138-3
Bernheim A., Berger R., Lenoir G.M.
Cytogenetic studies on Burkitt's lymphoma cell lines.
Cancer Genet. Cytogenet. 8:223-229(1983)

PubMed=3934070
Lenoir G.M., Vuillaume M., Bonnardel C.
The use of lymphomatous and lymphoblastoid cell lines in the study of Burkitt's lymphoma.
IARC Sci. Publ. 60:309-318(1985)

PubMed=3027441; DOI=10.1093/jnci/78.2.235
Cohen J.H.M., Revillard J.-P., Magaud J.-P., Lenoir G.M., Vuillaume M., Manel A.-M., Vincent C., Bryon P.-A.
B-cell maturation stages of Burkitt's lymphoma cell lines according to Epstein-Barr virus status and type of chromosome translocation.
J. Natl. Cancer Inst. 78:235-242(1987)

PubMed=8108117
Albert T., Urlbauer B., Kohlhuber F., Hammersen B., Eick D.
Ongoing mutations in the N-terminal domain of c-Myc affect transactivation in Burkitt's lymphoma cell lines.
Oncogene 9:759-763(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_M640
Encyclopedic resources Wikidata; Q54797102
Polymorphism and mutation databases Cosmic; 2804858
Entry history
Entry creation05-Nov-2013
Last entry update02-May-2024
Version number15