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Cellosaurus HEK (CVCL_M624)

[Text version]
Cell line name HEK
Synonyms Human Embryonic Kidney; HEK-1; HEK-RLV
Accession CVCL_M624
Resource Identification Initiative To cite this cell line use: HEK (RRID:CVCL_M624)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=1246601; PubMed=4469665; PubMed=4864103; PubMed=20143388). Originally thought to originate from an embryonic kidney.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00063.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Caution: Not to be confused with cell line HEK293 (Cellosaurus=CVCL_0045).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related endocervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Children:
CVCL_M625 (HEK/HRV)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages Info; ICLAC; -; https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=4864103
Stanley Michael Gartler;
Genetic markers as tracers in cell culture.
Natl. Cancer Inst. Monogr. 26:167-195(1967)

CLPUB00339
Sami Ali Mayyasi, Karl A. Traul, Claude F. Garon, Bruce S. Wright;
Antigenics characteristics of Rauscher virus cultivated in human embryonic kidney cells.
Proc. Am. Assoc. Cancer Res. 11:54.211-54.211(1970)

PubMed=4621398; DOI=10.3181/00379727-139-36065
Karl A. Traul, Sami Ali Mayyasi, Claude F. Garon, George Schidlovsky, Laurette M. Bulfone;
Antigenic comparison of Rauscher murine leukemia virus cultivated in human embryo and mouse cells.
Proc. Soc. Exp. Biol. Med. 139:10-14(1972)

PubMed=4137948
Robert J. Eckner, Elizabeth S. Priori, Edwin A. Mirand, Leon Dmochowski;
Studies on the biological and antigenic properties of ESP-1 type C virus particles.
Cancer Res. 34:2521-2529(1974)

PubMed=4469665; DOI=10.1126/science.184.4141.1093
Walter Anthony Nelson-Rees, Robert R. Flandermeyer, Paula K. Hawthorne;
Banded marker chromosomes as indicators of intraspecies cellular contamination.
Science 184:1093-1096(1974)

PubMed=1246601; DOI=10.1126/science.1246601
Walter Anthony Nelson-Rees, Robert R. Flandermeyer;
HeLa cultures defined.
Science 191:96-98(1976)

PubMed=20143388; DOI=10.1002/ijc.25242
Amanda Capes-Davis, George Theodosopoulos, Isobel Atkin, Hans Gunther Drexler, Arihiro Kohara, Roderick A.F. MacLeod, John R.W. Masters, Yukio Nakamura, Yvonne A. Reid, Roger Robert Reddel, Robert Ian Freshney;
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cross-references
Biological sample resources BioSample; SAMN03151703
Encyclopedic resources Wikidata; Q54882276
Entry history
Entry creation05-Nov-2013
Last entry update10-Apr-2025
Version number19